An Extremely Rare Case of Gastric Subepithelial Tumor: Gastric Endometriosis

Jong Kun Ha, Cheol Woong Choi, Hyung Wook Kim, Dae Hwan Kang, Su Bum Park, Su Jin Kim, Jeong Beom Hong
Clinical endoscopy · 2015 · vol. 48(1) , pp. 74 · doi:10.5946/ce.2015.48.1.74 · PMID:25674531 · PMC4323438 · W2147667411
article OA: gold CC0 ⤵ 8 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This report details a rare case of endometriosis occurring outside the pelvic cavity, specifically presenting as a subepithelial tumor within the stomach.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-08 ⓘ

This paper reports an extremely rare case of gastric endometriosis presenting as a 2-cm subepithelial gastric mass in a 44-year-old woman identified during routine screening; the patient was asymptomatic and had no notable medical or family history. Using gastroscopy and endoscopic ultrasonography (with CT to characterize an endophytic hypodense submucosal lesion), the lesion was suspected to be a gastrointestinal stromal tumor, and because the patient declined preoperative histologic confirmation (EUS-FNA or incision biopsy), laparoscopic-assisted distal gastrectomy was performed. Histopathology showed endometriosis with endometrial glands and hemosiderin-laden macrophages within the muscular layer near intramural hemorrhagic cysts, and follow-up over about 2 years found no recurrence or abnormal structural findings. The paper’s key limitation is its reliance on a single case with no preoperative tissue diagnosis and limited duration of observation. This paper is centrally about endometriosis — it details gastric endometriosis mimicking a subepithelial tumor.

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Abstract

Endometriosis is a disease characterized by the presence of endometrial tissue outside of the uterine cavity. It is common in women of childbearing age, and is most frequently located in the pelvic cavity. Approximately 10% of endometriosis cases occur outside of the pelvic cavity in locations such as the intestines, genitourinary system, kidneys, lungs, and skin. However, there have been few reports of endometriosis in the stomach. Here, we report a rare case of endometriosis that presented as a subepithelial stomach tumor.

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endometriosis

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