Estrogen Biosynthesis and Its Regulation in Endometriosis
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⤵ 10 in-corpus citations
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This review examines the mechanisms of estrogen biosynthesis and its regulation within endometriotic tissues, which are characterized by elevated local estrogen production.
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Abstract
Endometriosis is a common benign gynecological disorder with an enigmatic etiology and pathogenesis. It affects approximately 10% women of reproductive age. Although its etiology and pathogenesis remain poorly understood, it is characterized by the elevated local production of estrogen in the endometriotic tissues. In this paper, we review the mechanisms of estrogen biosynthesis and its regulation in endometriosis.
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References (2)
- Estrogen biosynthesis in endometriosis: molecular basis and clinical relevance via openalex
- Stromal cells of endometriosis fail to produce paracrine factors that induce epithelial 17β-hydroxysteroid dehydrogenase type 2 gene and its transcriptional regulator Sp1: a mechanism for defective estradiol metabolism via openalex
Cited by (10)
- NUTRIÇÃO COMO COADJUVANTE NO TRATAMENTO DA ENDOMETRIOSE: UMA REVISÃO SISTEMÁTICA 2025
- Zinc(II) niflumato complex effects on MMP activity and gene expression in human endometrial cell lines 2021
- Potential Therapeutic Options and Perspectives for Alleviation of Endometrial Estrogen Dominance and Progesterone Resistance in Endometriosis 2021
- Endometriosis - Recent Advances, New Perspectives and Treatments 2021
- Mouse model for endometriosis is characterized by proliferation and inflammation but not epithelial-to-mesenchymal transition and fibrosis 2020
- Molecular profile of eutopic and ectopic endometrium in endometriosis 2020
- Spatial and temporal changes in the expression of steroid hormone receptors in mouse model of endometriosis 2020
- An assessment of the multifactorial profile of steroid-metabolizing enzymes and steroid receptors in the eutopic endometrium during moderate to severe ovarian endometriosis 2019
- Ontogeny and expression profiles of steroid hormone receptors in a mouse model of endometriosis 2019
- An assessment of the multifactorial profile of steroid-metabolizing enzymes and steroid receptors in the eutopic endometrium during moderate to severe ovarian endometriosis 2019
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- last seen: 2026-06-10T17:14:06.276822+00:00
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