Non-invasive diagnostics of endometriosis: review of modern biomarkers of peripheral blood and endometrium
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Abstract
Endometriosis is a chronic progressing estrogen-dependent disease with a high incidence among females characterized by pelvic pain (40-80%) and infertility (25-80%). Aim. To analyze and estimate the modern literature data on the possibility of using potential biomarkers of endometriosis in its non-invasive diagnostics. In recent years, researchers have made significant advances in understanding the disease-specific molecular pathways that regulate the development of ectopic foci of endometriosis, by examining the blood, peritoneal fluid, and eutopic endometrium in women with the disease. Along with understanding the pathophysiology of endometriosis, the question of finding an adequate biomarker that will provide an effective early non-invasive diagnosis of endometriosis and, accordingly, preserve the reproductive health of millions of women, remains relevant. Conclusion. Most reasonable in diagnostics of endometriosis is a combination of different biomarkers that also minimizes false positive and negative results in differential diagnosis.
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References (10)
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Cited by (6)
- Actualization of differential diagnosis of chronic pelvic pain syndrome in women of reproductive age 2023
- POTENTIAL ВIOMARKERS OF ENDOMETRIOSIS: THE SEARCH IS UNDERWAY 2023
- Modern concepts o f endometrial receptivity in endometriosis-associated infertility (analytical review) 2023
- CYFRA 21-1 Protein - a Potential Marker of Endometriosis 2023
- ENDOMETRIOSIS ASSOCIATED INFERTILITY: VERSIONS AND COUNTERVERSIONS 2023
- Endometrioid disease is a modern view of the problem 2022
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- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
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