Reduction of adhesion reformation after laparoscopic endometriosis surgery: a randomized trial with an oxidized regenerated cellulose absorbable barrier
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⤵ 20 in-corpus citations
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An oxidized regenerated cellulose barrier significantly reduced adhesion reformation after laparoscopic surgery for endometriosis compared to surgery alone in a randomized trial.
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Abstract
OBJECTIVE: To evaluate the effectiveness of an oxidized regenerated cellulose absorbable barrier (Interceed [TC7] Absorbable Adhesion Barrier) in the reduction of adhesion reformation after laparoscopic surgery for endometriosis.
METHODS: Thirty-two premenopausal nonpregnant women who had severe endometriosis and complete posterior cul-de-sac obliteration and were undergoing laparoscopic surgery were randomly assigned to either surgery alone or surgery and Interceed. None of the subjects received any other treatment for adhesion prevention. Second-look laparoscopy was performed 12-14 weeks after laparoscopic surgery by an investigator blinded to the treatment, and the incidence of adhesion-free subjects was assessed.
RESULTS: Twelve of 16 (75%) women treated with the oxidized regenerated cellulose barrier were free of adhesions, compared with two of 16 (12.5%) controls, a statistically significant difference (P < .05).
CONCLUSION: The oxidized regenerated cellulose absorbable barrier significantly reduces adhesion reformation after laparoscopic surgery for endometriosis.
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Cited by (20)
- Adhesion prevention after endometriosis surgery - results of a randomized, controlled clinical trial with second-look laparoscopy 2021
- Adolescent Endometriosis: Fertility Outcomes 2020
- Barrier agents for adhesion prevention after gynaecological surgery 2020
- Effectiveness of ovarian suspension in preventing postoperative ovarian adhesions in patients with severe pelvic endometriosis—a case-control study 2019
- [Minimal and mild endometriosis: Impact of the laparoscopic surgery on pelvic pain and fertility. CNGOF-HAS Endometriosis Guidelines] 2018
- Barrier agents for adhesion prevention after gynaecological surgery 2015
- Adhesion prevention in endometriosis: a neglected critical challenge 2012
- Surgical measures for endometriosis-related infertility: a plea for research 2011
- Clinical management of endometriosis 2011
- Laparoscopic management of endometriosis: comprehensive review of best evidence 2009
- Ovarian endometrioma: postoperative adhesions following bipolar coagulation and suture 2008
- [Guidelines for the management of painful endometriosis] 2007
- Conservative surgical management of endometriosis in women with pelvic pain 2006
- La diagnosi di endometriosi 2005
- Transient abdominal ovariopexy for adhesion prevention in patients who underwent surgery for severe pelvic endometriosis 2004
- Transient abdominal ovariopexy for adhesion prevention in patients who underwent surgery for severe pelvic endometriosis 2004
- The role of laparoscopy in the chronic pelvic pain patient 2003
- Endometriosis, Endometrioma, and the Problem of Adhesions 2000
- Peritoneal Endometriosis 2000
- The evidence for the management of endometriosis 1998
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- europepmc
- last seen: 2026-10-16T06:09:50.462052+00:00
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- pubmed
- last seen: 2026-10-08T21:58:54.395363+00:00
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