Iron overload–modulated nuclear factor kappa-B activation in human endometrial stromal cells as a mechanism postulated in endometriosis pathogenesis

Carlos Patricio Alvarado-Díaz, Marco T. Núñez, Marco Tulio Núñez, Luigi Devoto, Reinaldo González-Ramos
Fertility and sterility · 2014 · vol. 103(2) , pp. 439–447 · doi:10.1016/j.fertnstert.2014.10.046 · PMID:25500022 · W2072916560
article OA: green CC0 ⤵ 21 in-corpus citations
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-08 ⓘ

Iron overload activated the NF-kappa B pathway in human endometrial stromal cells, increasing ICAM-1 expression and secretion, suggesting a role in endometriosis pathogenesis.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometrium Endometrium Iron Overload NF-kappa B Adult Amides Amides Cells, Cultured Endometriosis Endometriosis Endometrium Endometrium Female Ferric Compounds Ferric Compounds Humans Iron Overload Iron Overload NF-kappa B

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Cited by (21)

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