Endometriosis in postmenopausal women without previous hormonal therapy: report of three cases

J. C. Rosa-e-Silva, Júlio César Rosa e Silva, Rosa-e-Silva JC, Bruno Ramalho de Carvalho, B R Carvalho, H de F Barbosa, Barbosa Hde F, Hermes de Freitas Barbosa, Omero Benedicto Poli‐Neto, O B Poli-Neto, Rosa-e-Silva AC, A C J S Rosa-e-Silva, Francisco José Cândido dos Reis, F. J. Candido-dos-Reis, Nogueira AA, AA Nogueira, A A Nogueira
Climacteric : the journal of the International Menopause Society · 2008 · vol. 11(6) , pp. 525–528 · doi:10.1080/13697130802490256 · PMID:18991080 · W2027335812
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This report details three postmenopausal women who developed endometriosis without prior hormone therapy, presenting with pelvic pain, ovarian cysts, abdominal masses, or rectovaginal nodules.

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Abstract

INTRODUCTION: Endometriosis is a benign, estrogen-dependent, chronic gynecological disorder associated with pelvic pain and infertility. The disease most commonly affects women during the reproductive age, although postmenopausal patients do rarely present it. These rare occurrences are generally associated with hormonal use. MATERIAL AND METHODS: We present three cases of endometriosis in postmenopausal patients who have no history of hormone therapy and no previous history of endometriosis or infertility. CASE REPORTS: In case 1, a 62-year-old woman presented with acyclic pelvic pain and a left ovarian homogeneous cystic mass. After laparoscopic salpingoophorectomy and histological analysis, an ovarian endometriotic cyst was confirmed. In case 2, a 78-year-old woman presented with a painful abdominal wall mass that was confirmed by ultrasound and tomography. Her past medical history included an abdominal hysterectomy 20 years prior to the discovery of this mass. The lesion was surgically excised and histological analysis showed areas of endometrial stroma and glands surrounded by fibrosis, compatible with endometriosis. In case 3, a 54-year-old woman presented with chronic pelvic pain and a nodule in the rectovaginal septum was noted during gynecological examination. Menopause occurred at 48 years of age. She had no previous dysmenorrhea. Ultrasound confirmed the nodule in the rectovaginal septum. The patient was submitted to a diagnostic colonoscopy that revealed a friable lesion, which was subsequently biopsied. The histological diagnosis was endometriosis. CONCLUSIONS: These three cases of postmenopausal endometriosis support the celomic metaplasia theory for the genesis of this disease.

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Condition tags

endometriosischronic_pelvic_paindysmenorrheainfertility

MeSH descriptors

Endometriosis Endometriosis Postmenopause Postmenopause Abdominal Pain Abdominal Pain Abdominal Pain Aged Aged Biopsy Biopsy Endometriosis Endometriosis Endometriosis Female Female Humans Humans Middle Aged Middle Aged

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References (19)

Cited by (18)

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