FLORID ADNEXAL POLYPOID ENDOMETRIOSIS ASSOCIATED WITH VERY HIGH SERUM CA-125 LEVELS MIMICKING OVARIAN MALIGNANCY (CASE REPORT)

Nagaraj Srinivas Ghante, Chalageri Anitha, Gupta Anjana, Manjula Vijayanand
In: Iranian journal of pathology · 2014 · vol. 9(1) , pp. 71–76 · W2345708507
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⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

This case report describes florid polypoid endometriosis presenting with bulky pelvic disease and extremely high serum CA-125 levels, mimicking ovarian malignancy before histopathological confirmation.

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Abstract

We report a case of florid polypoid endometriosis presenting with advanced bulky disease in pelvis with serum CA – 125 levels of 7844U/ml. The extent of tumor, CT scan findings, elevated serum CA – 125 levels were suggestive of ovarian malignancy. Histopathology demonstrated endometrial glands and stroma. Glands were neither crowded nor complex and were separated by a fibromatous stroma that contained endometrial stromal cells. These features were consistent with diagnosis of polypoid endometriosis, a recently described entity with a clinical presentation completely different from conventional endometriosis. Our case emphasizes the association of high levels of CA – 125 with benign gynaecologic conditions.

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endometriosis

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