Multifocal polypoid endometriosis in a young woman simulating vaginal and pelvic neoplasm

Seema Kaushal, Vatsla Dadhwal, Sandeep Mathur, Sandeep R Mathur, Ruma Ray, Prashant Durgapal, Deepika Deka
Journal of clinical pathology · 2010 · vol. 63(5) , pp. 452–454 · doi:10.1136/jcp.2009.073312 · PMID:20299388 · W2126211686
article OA: closed CC0 ⤵ 8 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This paper describes a 27-year-old woman whose vaginal and pelvic masses, initially suspected to be neoplastic, were diagnosed as multifocal polypoid endometriosis based on histopathology and immunohistochemistry.

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Abstract

A 27-year-old nulliparous woman presented with large finger-like projections protruding from her vagina. Intraoperatively there were deposits in the pouch of Douglas. Clinical presentation and history of vaginal bleeding suggested malignancy. Histopathology of both the vaginal and pouch of Douglas masses showed endometrial glands and stroma. There was no architectural complexity or cytological atypia of glands or stroma. Immunohistochemistry for oestrogen receptor, progesterone receptor and CD10 was positive. Based on morphological and immunohistochemical findings, multifocal polypoid endometriosis was diagnosed; this is a recently described entity having a clinical presentation and age range completely different from conventional or non-polypoid endometriosis. Although an association between tamoxifen use, unopposed oestrogen therapy and polypoid endometriosis has been suggested, the patient had no history of tamoxifen or oestrogen intake. Polypoid endometriosis should be part of the differential diagnosis in young women presenting with vaginal growth.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Pelvic Neoplasms Peritoneal Diseases Polyps Vaginal Diseases Adult Diagnosis, Differential Douglas' Pouch Douglas' Pouch Endometriosis Female Humans Pelvic Neoplasms Peritoneal Diseases Polyps Vaginal Diseases Vaginal Neoplasms Vaginal Neoplasms

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (10)

Cited by (8)

Source provenance

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