Endometrial stromal sarcoma arising from polypoid endometriosis

Fabio Carbone, Manou Manpreet Kaur, Aik Yong Chok, Christos Kontovounisios, Thomas Ind, Shahnawaz Rasheed
International journal of surgery case reports · 2020 · vol. 72(C) , pp. 537–540 · doi:10.1016/j.ijscr.2020.06.062 · PMID:32698283 · PMC7327825 · W3036041073
article OA: gold CC0 ⤵ 6 in-corpus citations
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Abstract

BACKGROUND: Polypoid endometriosis (PE) is a rare and uncommon variant of endometriosis that may present as a polypoid mass that simulates a malignant neoplasm. Typically, PE develops locally as a large benign pelvic mass. However, it may sometimes conceal a malignant disease in its context. CASE PRESENTATION: A 53 years old, nulliparous lady, had been treated over a 10-year period for recurrent and symptomatic polypoid endometriosis of the pelvis. During this time, she underwent four surgical resections, the final one being a total pelvic exenteration, with histology demonstrating the presence of a rare myxoid low grade Endometrial Stromal Sarcoma (ESS) that had arisen in PE. CONCLUSION: PE is a rare variant growth pattern of endometriosis which may involve different pelvic organs and can mimic a malignant mass in the pelvis. It mostly affects women in their peri- or post-menopausal age and it is not always related to hormonal therapy. Malignances, such as Endometrial Stromal Sarcoma in this case, can arise in the context of PE and their diagnosis can be challenging. Surgical excision may constitute radical multi-organ resection, particularly for recurrent and symptomatic cases. However, the recurrence rates after surgery can be significant.

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endometriosis

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