LINC01541 overexpression attenuates the 17β-Estradiol-induced migration and invasion capabilities of endometrial stromal cells

article OA: bronze CC0 ⤵ 11 in-corpus citations
AI-generated summary by claude@2026-06, 2026-06-08

This study found that LINC01541 overexpression inhibited the 17β-estradiol-induced migration and invasion of endometrial stromal cells by affecting EMT-related proteins.

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Abstract

ESCs: endometrial stromal cells; 17β-E2: 17β-Estradiol; EMT: epithelial-mesenchymal transition; CASP3: caspase 3; BCL2: B cell leukemia/lymphoma 2; VEGFA: vascular endothelial growth factor A; lncRNA: long non-coding RNA; GAPDH: glyceraldehyde-3-phosphate dehydrogenase; RT-qPCR: reverse transcription-quantitative polymerase chain reaction.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis RNA, Long Noncoding Cell Movement Cells, Cultured Endometriosis Endometriosis Endometrium Endometrium Estradiol Female Humans RNA, Long Noncoding Stromal Cells Stromal Cells

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References (42)

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Source provenance

europepmc
last seen: 2026-06-11T06:19:48.454388+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:23:01.605684+00:00
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