Cytogenetic studies in endometriosis tissue

Astrid Dangel, A Dangel, Dangel A, Michael T. Medchill, M T Medchill, Medchill MT, Davis G, G Davis, Gordon B. Davis, A M Meloni, Meloni AM, Aurelia M. Meloni, Sandberg AA, Avery A. Sandberg, A A Sandberg
Cancer genetics and cytogenetics · 1994 · vol. 78(2) , pp. 172–174 · doi:10.1016/0165-4608(94)90086-8 · PMID:7828149 · W1992220939
article OA: closed CC0 ⤵ 17 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This paper investigated the cytogenetic profile of endometriosis tissue, identifying specific chromosomal abnormalities present in the samples.

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Abstract

We analyzed 45 pelvic endometrial implants from 42 patients between the ages of 14 and 40 years to investigate whether cytogenetic abnormalities were present in these samples. Chromosomal abnormalities have been described in benign tumors of the female genital tract, such as uterine leiomyomas and endometrial polyps. Furthermore, heritable factors have been postulated to influence a woman's susceptibility to develop endometrial tissue implants outside the uterine cavity. To study whether these factors result in or are associated with chromosomal changes, endometriosis cells were analyzed cytogenetically after short-term culture. No consistent chromosome abnormalities were observed in any of the cases analyzed.

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Condition tags

endometriosis

MeSH descriptors

Chromosome Aberrations Endometriosis Peritoneal Diseases Adult Endometriosis Female Humans Karyotyping Peritoneal Diseases

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (27)

Cited by (17)

Source provenance

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License: CC0 · commercial use OK