A unique clonal chromosome 2 deletion in endomyometriosis

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This paper describes a unique clonal deletion on chromosome 2 identified in patients with endomyometriosis.

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Abstract

The cytogenetic analysis of a short-term culture from a so-called endomyometriosis revealed a unique clonal del(2)(p21). The embryologic origin of this uterine-like mass is controversial. The finding of a clonal chromosome aberration favors the proliferation hypothesis and suggests that endomyometriosis is a true neoplasm and that a somatic mutation might be involved in the etiology of this lesion.

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