Endomyometriosis arising in the uterosacral ligament: A case report including a literature review and immunohistochemical analysis

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This case report describes endomyometriosis in a uterosacral ligament containing hormone-dependent epithelial, stromal, and smooth muscle cells with high proliferation activity.

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Abstract

We report a case of endomyometriosis arising in the left uterosacral ligament of a 29-year-old woman. The central cavity of the uterine-like mass was lined by pseudo-stratified columnar epithelium and endometrial stroma. The wall of the cyst consisted of bundles of smooth muscle cells. Immunohistochemical analysis demonstrated both alpha-estrogen receptor and progesterone receptor immunoreactivities in the epithelial, stromal and smooth muscle cells. A relatively high proliferating activity was also demonstrated in these cells by Ki-67 immunostaining. These findings suggest that the mass was hormone dependent and had a relatively rapid evolution.

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