The Impact of Endometriosis on Reproductive Outcomes in ART Cycles

Motahare Ebrahimpoor, Razieh Dehghani Firouzabadi, Atiyeh Javaheri, Farimah Shamsi, Saeideh Dashti
Advanced biomedical research · 2024 · vol. 13(1) , pp. 89 · doi:10.4103/abr.abr_436_23 · PMID:39512416 · PMC11542699 · W4402777310
article OA: gold CC0 ⤵ 3 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study found that women with endometriosis undergoing ART had fewer retrieved oocytes and embryos, with lower chemical and clinical pregnancy rates compared to controls.

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Abstract

BACKGROUND: Endometriosis is defined as the existence of endometrial glands and stroma outside the uterine cavity. This disease is responsible for about 15% of the indications for assisted reproductive technologies (ART). MATERIALS AND METHODS: This study is a retrospective cross-sectional study on 1382 women aged 18-42 who underwent ART in Yazd Reproductive Sciences Institute during 2018-2022. Women were divided into two groups: women with endometriosis (N = 173) and women with a tubal factor or unexplained infertility as the control group (N = 1209). Chemical and clinical pregnancy rates and live birth rates were compared. RESULTS: Women with endometriosis had significantly (P < 0.001) lower retrieved oocytes (7.73 ± 5.52 vs 11.53 ± 7.46), metaphase II oocytes (6.27 ± 4.72 vs 9.37 ± 6.62), and the total number of obtained embryos (3.95 ± 3.52 vs 6.13 ± 5.02). Chemical (P = 0.001) and clinical (P = 0.028) pregnancy rates were lower in women with endometriosis, while live birth rates showed no difference between the two groups (P = 0.069). CONCLUSION: The findings of this study showed that endometriosis can disturb reproductive outcomes after ART.

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endometriosisinfertility

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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