Advanced biomedical research

Adv Biomed Res · ISSN (print) 2277-9175 · 32 papers in corpus
rct 2026
doi:10.4103/abr.abr_286_25 ·PMID:41809848

BACKGROUND: Decreased Ovarian Reserve (DOR) is a significant challenge in infertility treatment. This study, which compared the effects of Novel Dual Trigger and Delayed Human Chorionic Gonadotropin (HCG), holds promise for improving IVF ou…

2026
2026
rct 2025
doi:10.4103/abr.abr_530_24 ·PMID:41669291

BACKGROUND: Ectopic pregnancy (EP) is one of the critical health conditions worldwide. Letrozole, an aromatase inhibitor that suppresses peripheral conversion of androgens to estrogens, has recently been introduced as a low-cost and minimal…

lab-animal 2025
doi:10.4103/abr.abr_512_24 ·PMID:41669294

BACKGROUND: AngiomiRs, a group of microRNAs, target angiogenesis-related genes such as VEGF. Angiogenesis is crucial for endometrial receptivity and all stages of pregnancy. Research indicates that steroid concentrations can affect molecula…

rct 2025
doi:10.4103/abr.abr_69_24 ·PMID:40390812

BACKGROUND: Vulvovaginal Candidiasis (VVC) is a prevalent and complex health issue in women. With the rising resistance to synthetic antifungal medications, there is a growing emphasis on exploring natural remedies that minimize disruption …

observational 2024
doi:10.4103/abr.abr_66_23 ·PMID:39411692

BACKGROUND: Polyps are a common diagnosis in women of different ages. They can cause a variety of symptoms from bleeding to infertility and can even be the progenitor for malignancies. MATERIALS AND METHODS: This was a retrospective cohort…

observational 2024
doi:10.4103/abr.abr_436_23 ·PMID:39512416

BACKGROUND: Endometriosis is defined as the existence of endometrial glands and stroma outside the uterine cavity. This disease is responsible for about 15% of the indications for assisted reproductive technologies (ART). MATERIALS AND MET…

rct 2023
doi:10.4103/abr.abr_253_22 ·PMID:37434944

BACKGROUND: The quality of the luteal phase is the most important issue affecting pregnancy outcomes in assisted reproductive technology (ART). Luteal-phase support with the administration of gonadotropin-releasing hormone (GnRH) agonist or…

observational 2023
doi:10.4103/abr.abr_100_23 ·PMID:38073732

BACKGROUND: CA125 levels show a variation in premenopausal women during the menstrual cycle. Moreover, various modifiable and non-modifiable factors affect its value which needs to be taken into account while interpreting the results. The s…

other 2023
doi:10.4103/abr.abr_264_22 ·PMID:37564454

BACKGROUND: Evaluation of ovarian tumors based on tumor markers could have high clinical importance. In this study, we aimed to assess the predictive value of HE4 and Risk of Ovarian Malignancy Algorithm (ROMA) compared to CA-125 in the Mal…

other 2023
doi:10.4103/abr.abr_86_22 ·PMID:37288024

BACKGROUND: Endometriosis is a female reproductive system disease in which the endometrial tissue is found in other women's organs. Various factors are effective in the development of endometriosis, and because of the interaction of genetic…

other 2023
doi:10.4103/abr.abr_411_21 ·PMID:36926432

BACKGROUND: Asherman syndrome is a controversial issue in obstetrics and gynecology without any consensus on its management and treatment. It is characterized by variable lesions inside the uterine cavity and also causes menstrual irregular…

other 2023
doi:10.4103/abr.abr_200_22 ·PMID:37434942

BACKGROUND: According to the bioinformatics analyses and previous studies, bone morphogenetic protein receptor type 1B (BMPR1B) dysregulation could remarkably affect breast cancer (BC) status as a potential biomarker and tumor suppressor. T…

case-report 2022
doi:10.4103/abr.abr_32_21 ·PMID:36518855

Lipoma is an uncommon mesenchymal tumor of the colon. They are typically symptom free, the large lipomas within the colon are rare, and can cause obstruction, bleeding, or intussusception. Intussusception is comparatively common in pediatri…

diagnostic-accuracy 2022
doi:10.4103/abr.abr_164_20 ·PMID:35386543

BACKGROUND: CA125 is the most used tumor marker for ovarian cancer monitoring and diagnosis. This study aimed to evaluate the capacity to predict malignancy in women with adnexal tumors using CA125 measurement and ultrasound criteria before…

nonrandomized-trial 2022
doi:10.4103/abr.abr_100_20 ·PMID:35386535

BACKGROUND: Sacroiliac pain is one of the causes of low back pain, representing with discomfort and tenderness in the sacroiliac joint. Interventional procedures might be beneficial in cases unresponsive to medical treatments. Here, we aime…

rct 2022
doi:10.4103/abr.abr_56_21 ·PMID:36325167

BackgroundHysterectomy is one of the most common gynecology surgeries. This study aimed to compare perioperative bleeding in transabdominal and transvaginal hysterectomy.Materials and methodsThis prospective, double-blind, randomized, contr…

lab-animal 2018
doi:10.4103/abr.abr_225_16 ·PMID:29456987

BACKGROUND: Intra-abdominal adhesions after surgery are usually in the form of bands and can annoy the patient throughout life causing repeated surgical procedures. Therefore, any action to prevent adhesions after surgery can increase longe…

diagnostic-accuracy 2018
doi:10.4103/abr.abr_71_17 ·PMID:30050889

BACKGROUND: Infertility, as one of the most common gynecological disorders, affects many people worldwide. To choose the clinical treatment, correct assessment of tubal patency can provide an important clue; therefore, it is considered as o…

observational 2018
doi:10.4103/abr.abr_58_18 ·PMID:30211132

BackgroundOne of the consequences of toxoplasmosis is the risk of passing it from mother to fetus and the onset of congenital toxoplasmosis during pregnancy. The purpose of this study was to evaluate the B1 gene of Toxoplasma gondii in the …

observational 2017
doi:10.4103/2277-9175.219416 ·PMID:29285481

BACKGROUND: Acute pelvic inflammatory disease (PID) is a common reason for infertility. This study aimed to evaluate the frequency distribution of endometritis in women with unexplained infertility and comparison with frequency distribution…

lab-animal 2017
doi:10.4103/2277-9175.218029 ·PMID:29279836

BACKGROUND: Angiogenesis plays a major role in endometrial receptivity and thickening of the endometrium immediately before implantation. The aim of the present work was to evaluate the antiangiogenic properties of epigallocatechin-3-gallat…

lab-animal 2017
doi:10.4103/abr.abr_79_17 ·PMID:29387675

BACKGROUND: Ovarian angiogenesis (OA) remains in lifetime and normal ovarian function depends to this continual remodeling of a complex vascular system. Endometrial thickness (ET) is one of the strongest predictors of successful implantatio…

other 2015
doi:10.4103/2277-9175.164006 ·PMID:26605221

BACKGROUND: Serum antimullerian hormone (AMH) proposed to be a reliable marker of ovarian reserve; the aim of this study was to evaluate the influence and value of laparoscopic management in endometriosis as measured by serum AMH levels. M…