B lymphocyte stimulator −817C>T promoter polymorphism and the predisposition for the development of deep infiltrating endometriosis

de Graaff AA, Aisha A de Graaff, A. A. de Graaff, Dunselman GA, Gerard A J Dunselman, Delvoux B, Bert Delvoux, van Kaam KJ, Kim J. van Kaam, Luc J M Smits, Luc Smits, Smits LJ, Andrea Romano
Fertility and sterility · 2009 · vol. 94(3) , pp. 1108–1110 · doi:10.1016/j.fertnstert.2009.10.041 · PMID:20004378 · W2094439303
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The BLyS -817C>T promoter polymorphism was less frequent in women with deep infiltrating endometriosis compared to control groups, indicating a potential protective effect.

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Abstract

The prevalence of the BLyS -817C>T polymorphic variant among women with either deep infiltrating endometriosis or adenomyosis compared with a group of gynecologic patients without symptomatic endometriosis and a group of healthy women was assessed in this study. Patients with deep infiltrating endometriosis had less often a BLyS -817C/T genotype as compared with the reference group, with an odds ratio of 0.50 (95% confidence interval 0.27-0.93 versus the C/C genotype).

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Condition tags

endometriosisdie_deep_infiltrating

MeSH descriptors

B-Cell Activating Factor Endometriosis Peritoneal Diseases Polymorphism, Single Nucleotide Polymorphism, Single Nucleotide Promoter Regions, Genetic Promoter Regions, Genetic Adult B-Cell Activating Factor Case-Control Studies Endometriosis Endometriosis Female Gene Frequency Genetic Predisposition to Disease Humans Middle Aged Odds Ratio Peritoneal Diseases Peritoneal Diseases

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (11)

Cited by (9)

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