B lymphocyte stimulator −817C>T promoter polymorphism and the predisposition for the development of deep infiltrating endometriosis

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The BLyS -817C>T promoter polymorphism was less frequent in women with deep infiltrating endometriosis compared to control groups, indicating a potential protective effect.

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Abstract

The prevalence of the BLyS -817C>T polymorphic variant among women with either deep infiltrating endometriosis or adenomyosis compared with a group of gynecologic patients without symptomatic endometriosis and a group of healthy women was assessed in this study. Patients with deep infiltrating endometriosis had less often a BLyS -817C/T genotype as compared with the reference group, with an odds ratio of 0.50 (95% confidence interval 0.27-0.93 versus the C/C genotype).

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Condition tags

endometriosisdie_deep_infiltrating

MeSH descriptors

B-Cell Activating Factor Endometriosis Peritoneal Diseases Polymorphism, Single Nucleotide Polymorphism, Single Nucleotide Promoter Regions, Genetic Promoter Regions, Genetic Adult B-Cell Activating Factor Case-Control Studies Endometriosis Endometriosis Female Gene Frequency Genetic Predisposition to Disease Humans Middle Aged Odds Ratio Peritoneal Diseases Peritoneal Diseases

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (11)

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Source provenance

europepmc
last seen: 2026-07-29T06:27:48.050232+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:13:53.633898+00:00
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