Editorial: The impact of endometriosis

Adriana Luckow Invitti, Invitti AL, Nogueira, Adriana, Demetriou L, Lysia Demetriou
Frontiers in global women's health · 2023 · vol. 4 , pp. 1190974 · doi:10.3389/fgwh.2023.1190974 · PMID:37284278 · PMC10240052 · W4377205952
editorial OA: gold CC0 ⤵ 3 in-corpus citations
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-08 ⓘ

This editorial highlights the need for increased endometriosis research funding, awareness, and multidisciplinary approaches to improve diagnosis and treatment for millions affected by the disease.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-09 · read from full text ⓘ

This editorial describes the worldwide burden of endometriosis and summarizes an associated research topic aimed at improving understanding of disease impact, awareness, and management, including diagnostics, funding gaps, and emerging research directions. It highlights key limitations such as delayed diagnosis (about 8–12 years), underfunding relative to other chronic pain conditions, and ongoing needs for multidisciplinary care, while noting that standardization efforts (e.g., translations and cultural adaptations of the WERF EPHect Endometriosis Patient Questionnaire) enable cross-population comparisons without collection bias. The editorial also discusses included contributions such as a feasibility pilot of an Environmental Enrichment intervention in people with endometriosis during COVID-19-era disruptions, and a review of angiogenesis-related rationale for anti-angiogenic therapies beyond hormonal approaches. This paper is centrally about endometriosis — it is an editorial focused on the impact of endometriosis and an overview of research gaps and included studies.

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Abstract

This topic has highlighted the existing gaps in the understanding of the disease, its management, as well as the perception of endometriosis patients' on their treatments. It has been made clear that there is a need for more multidisciplinary research into the mechanisms underlying endometriosis as well as the development of new treatments and interventions. The topic reinforces the need for endometriosis awareness.Worldwide, endometriosis affects more than 190 million women and those assigned female at birth. This corresponds to 10% of women in reproductive age (Zondervan et al., 2020) who often experience clinical symptoms beyond menopause (Becker et al., 2022). Individuals suffering from the disorder may experience devastating effects on their quality of life, impacting both their physical and mental health resulting in the inability to perform even simple everyday tasks (Demetriou et al., 2022). Endometriosis also impacts people in the sufferer's environment including partners, family and work colleagues (Becker et al., 2022). One of the most common symptoms is disabling chronic pelvic pain, however, endometriosis is also the leading cause of infertility amongst women (Zondervan et al., 2020;Becker et al., 2021;Saunders and Horne, 2021). Although, it is difficult to calculate endometriosis' direct economic impact, it is comparable to type 2 diabetes, rheumatoid arthritis and Crohn's disease (Nnoaham et al., 2011;Zondervan et al., 2018). The aim of this topic was to present research that provides insights in the impact of the disease as well as promote endometriosis awareness. Following this objective, Ellis et al. (2022) provide an updated summary on endometriosis research and available diagnostic tools and treatments in clinics. They discuss the currently available funding in the field that falls short behind other chronic pain conditions such as Crohn's disease, leading to delayed advancements in the endometriosis field and increased economic burden for the patients. The authors strongly advocated that increased funding in endometriosis would benefit the 38 advancements in diagnosis and treatment particularly regarding currently evolving research fields such 39 as new biomarker analysis, nanomedicine and microbiota composition analysis. There is much space 40 for improvement regarding endometriosis awareness as well as the availability of multidisciplinary 41 treatments and diagnostic delay and accuracy.
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Ack

We would like to thank Emmanuel O. Adewuyi for his work and collaboration on developing, launching and managing this Research Topic.

Author

The authors have worked collaboratively on managing the topic and submitted articles. This editorial was led by ALI. ALI and LD have summarized the articles in the topic, discussed the main contributions to the field of each article. Both drafted and revised the work and approved the final version for publication.

Conflict

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Fn Group

1 www.endometriosisfoundation.org – Accessed March 6, 2023.

Publisher'S

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

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Condition tags

endometriosischronic_pelvic_paininfertility

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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