Difference in expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in patients with persistent ovarian cysts
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This study investigated the expression levels of matrix metalloproteinase-2 and matrix metalloproteinase-9 in patients diagnosed with persistent ovarian cysts.
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Abstract
Matrix metalloproteinase-1 (MMP-1), MMP-2, and MMP-9 expression with real-time quantitative polymerase chain reaction were analyzed in endometriotic and nonendometriotic ovarian cysts. Although MMP-1 was not detected, MMP-9 and MMP-2 were expressed in all of the cysts. In particular, in five of six nonendometriotic cysts (83.3%) MMP-2 expression was higher than in endometriotic cysts. These data may represent new molecular elements helpful in differential diagnosis of endometriotic lesions.
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Source provenance
- europepmc
- last seen: 2026-08-05T06:13:34.187606+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
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