Endometriosis screening in patients attending an IVF clinic: a proof-of-concept retrospective cohort study

Loren Méar, Charles Pineau, François Vialard, Juan-Felipe Velez de la Calle
Human fertility (Cambridge, England) · 2020 · vol. 25(2) , pp. 313–322 · doi:10.1080/14647273.2020.1795731 · PMID:32684058 · W3043324831
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This retrospective study found that sperm agglutination was significantly correlated with endometriosis and CA-125 levels in IVF patients, enabling a decision tree to identify high-risk individuals.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-09 ⓘ

I can’t access the paper’s study methods, results, or stated limitations because the provided text contains only a web-protection “making sure you're not a bot” interstitial, not the actual biomedical content. As a result, I’m unable to summarize what population was studied, how endometriosis screening was performed in the IVF clinic, or the key findings. The paper’s relationship to endometriosis: the title indicates it is about endometriosis screening in IVF patients, but the content necessary to confirm study details isn’t available in the text you provided.

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Abstract

Given that (i) endometriosis affects approximately 40% of women diagnosed with fertility problems and (ii) this condition may be an underestimated cause of idiopathic infertility, it is essential to identify high-risk patients for laparoscopic screening and reduce the diagnostic delay. We performed a retrospective analysis of 312 women (208 diagnosed with endometriosis and 104 controls) admitted to an in vitro fertilisation (IVF) unit in the city of Brest (France) between June 2007 and July 2014. As part of the women’s infertility treatment, levels of cancer antigen 125 (CA-125) were assayed in blood samples collected on the day of oocyte retrieval. Surplus serum was used to set up a new sperm agglutination test. It was observed that sperm agglutination was significantly correlated with endometriosis and CA-125 levels (p < 0.01 for both). By building a decision tree, we identified a subpopulation of patients with low CA-125 levels and a high risk of endometriosis. This proof-of-concept study constitutes a first step towards a high-quality, controlled, multi-centre trial. If our preliminary results are confirmed, the decision tree should improve the medical care given to women in IVF programmes by identifying potential endometriosis sufferers for laparoscopic examination and enabling them to be counselled about precautionary measures.

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Condition tags

endometriosisinfertility

MeSH descriptors

Endometriosis Endometriosis Infertility, Female Infertility, Female Cohort Studies Delayed Diagnosis Delayed Diagnosis Female Fertilization in Vitro Fertilization in Vitro Humans Male Pregnancy Pregnancy Rate Retrospective Studies

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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