Diagnostic Value of Serial Measurement of C-Reactive Protein in the Detection of a Surgical Complication after Laparoscopic Bowel Resection for Endometriosis

Mads Riiskjær, Axel Forman, Ulrik Schiøler Kesmodel, Kesmodel US, Andersen LM, Lars Maagaard Andersen, Ljungmann K, Ken Ljungmann, Mikkel Seyer-Hansen, Mikkel Seyer‐Hansen, Seyer-Hansen M
Gynecologic and obstetric investigation · 2016 · vol. 82(4) , pp. 410–416 · doi:10.1159/000447513 · PMID:27384530 · W2465869428
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Serial C-reactive protein measurements detected surgical complications after laparoscopic bowel resection for endometriosis, with a decrease from postoperative days 1 to 3 predicting an uncomplicated course.

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Abstract

AIMS: The study aimed to assess the diagnostic value of serial monitoring of biochemical inflammatory markers (C-reactive protein (CRP) and white blood cell (WBC) count) in the postoperative diagnosis of anastomotic leakage or ureteral injury after bowel resection for deep infiltrating endometriosis. METHODS: This is a review of prospectively collected data from 217 patients who underwent laparoscopic bowel resection for endometriosis from January 2009 to April 2015. Patients with an anastomotic leakage or ureteral injury were identified and classified. RESULTS: The frequency of anastomotic leakage requiring reoperation was 8.3%. The frequency of ureteral injury was 4.6%. Median time to diagnosis was 6 days for anastomotic leakage and 8 days for ureteral injury. The daily mean values of serum CRP were significantly higher in patients with a surgical complication starting at the second postoperative day (POD 2, p = 0.004). WBC was significantly higher (p < 0.05) on POD 2 and 3 in patients with a surgical complication. A decrease in CRP from POD 1 to 3 predicted an uncomplicated course in 92.1% of the cases. CONCLUSION: A decrease in CRP from POD 1 to 3 was an indicator of uncomplicated subsequent postoperative course. The test is recommended when early discharge after rectal resection for deep infiltrating endometriosis is considered.

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Condition tags

endometriosisdie_deep_infiltrating

MeSH descriptors

Colectomy C-Reactive Protein Endometriosis Laparoscopy Postoperative Complications Adult Adult Anastomotic Leak Anastomotic Leak Anastomotic Leak Biomarkers Biomarkers Biomarkers Colectomy Colectomy Colectomy C-Reactive Protein C-Reactive Protein Endometriosis Endometriosis

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (38)

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