Eye to the Future in Adenomyosis Research

Lisa M Halvorson, Linda C Giudice, Elizabeth A Stewart
Seminars in reproductive medicine · 2020 · vol. 38(02/03) , pp. 197–200 · doi:10.1055/s-0040-1721503 · PMID:33307559 · W3111013684
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This article summarizes current perspectives on future directions for basic, translational, and clinical research into adenomyosis, a poorly understood gynecologic disorder with significant morbidity.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This article is a narrative review summarizing the current state and future directions of basic, translational, and clinical research on adenomyosis, a disorder associated with dysmenorrhea, pelvic pain, heavy menstrual bleeding, infertility, and adverse pregnancy outcomes. Across epidemiology, risk factors, pathogenesis, pathophysiology, diagnosis, and treatment, it highlights substantial knowledge gaps and synthesizes recent concepts drawn from prior studies and research priorities. A stated limitation is that the paper summarizes “current thoughts” across many domains rather than presenting new original data. This paper is centrally about adenomyosis research — it outlines future directions spanning mechanisms, diagnosis, and treatment.

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Abstract

Adenomyosis is a poorly understood and clinically underappreciated gynecologic disorder associated with substantial morbidity including dysmenorrhea, pelvic pain, heavy menstrual bleeding, infertility, and poor pregnancy outcomes. Substantial gaps persist in our understanding of essentially all aspects of this disorder - epidemiology, risk factors, pathogenesis, pathophysiology, diagnosis, and treatment. In this article, we summarize current thoughts on future directions in basic, translational, and clinical adenomyosis research.

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Condition tags

adenomyosisdysmenorrheainfertility

MeSH descriptors

Adenomyosis Research Adenomyosis Adenomyosis Animals Disease Models, Animal Female Humans Pregnancy Research

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (24)

Cited by (6)

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