Endometrioid adenocarcinoma with squamous differentiation arising from ureteral endometriosis in a patient with no history of gonadal endometriosis
Case report
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This case report details an unusual instance of endometrioid adenocarcinoma with squamous differentiation that originated from ureteral endometriosis in a patient without a history of gonadal endometriosis.
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Abstract
BACKGROUND: Malignant transformation may occur in up to 1% of women with endometriosis and only 20% of these cases occur at extragonadal pelvic sites. Similarly, urinary tract endometriosis is rare and occurs in only 1% of all endometriotic lesions.
CASE: An endometrioid carcinoma with squamous differentiation arising from periureteral endometriosis presented as a pelvic mass encasing the right ureter. The patient had a history of total hysterectomy and bilateral salpingo-oopherectomy 8 years earlier because of bilateral serous benign cysts with right hemorrhagic corpus luteum and uterine fibroids, and has since been under unopposed estrogen replacement therapy for 5 years.
CONCLUSION: This is the second case of a malignancy arising in endometriosis presenting as an obstructive ureteral mass and the first case of a patient with this condition whose endometriosis is not consistent with a gonadal origin. An analysis of the case and related literature is presented together with the discussion of possible pathogenetic mechanisms.
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References (10)
- ENDOMETRIAL CARCINOMA OF THE OVARY, ARISING IN ENDOMETRIAL TISSUE IN THAT ORGAN via openalex
- Hyperestrogenism: a relevant risk factor for the development of cancer from endometriosis via openalex
- Left lateral predisposition of endometriosis and endometrioma via openalex
- Malignancy arising in extragonadal endometriosis: a case report and summary of the world literature via openalex
- Malignancy arising in extraovarian endometriosis during estrogen stimulation via openalex
- Ovarian and extraovarian endometriosis-associated cancer via openalex
- Surgical treatment of ureteral obstruction from endometriosis: our experience with thirteen cases via openalex
- Unilateral hydronephrosis resulting from intraluminal obstruction of the ureter by adenosquamous endometrioid carcinoma arising from disseminated endometriosis via openalex
- W2016891897 via openalex
- W1982582880 via openalex
Cited by (20)
- Case Report: Malignant transformation of deep infiltrating endometriosis: a report of two cases and literature review 2026
- Primary Retroperitoneal Carcinomas: New Insights into Pathogenesis and Clinical Management in Comparison with Ovarian Carcinomas and Carcinoma of Unknown Primary 2023
- Malignant Transformation of Postmenopausal Endometriosis: A Systematic Review of the Literature 2021
- A Rare Case of Combined Endometrioid Adenocarcinoma Arising from Uterine Adenomyosis and Clear Cell Carcinoma Arising from Parametrial Deep Endometriosis 2021
- Malignancies Associated with Extraovarian Endometriosis: A Literature Review 2021
- Endometriosis-associated Extraovarian Malignancies: A Challenging Question for the Clinician and the Pathologist 2020
- ♂♀ Müllerian Lesions of the Bladder: Endometriosis, Endosalpingiosis, Endocervicosis, and Müllerianosis 2019
- Retroperitoneal Endometrioid Carcinoma Arising from Ureteral Endometriosis 2019
- Ureteral endometriosis: a systematic review of epidemiology, pathogenesis, diagnosis, treatment, risk of malignant transformation and fertility 2018
- Post hysterectomy occurrence of endometrial adenocarcinoma in association with granulosa cell tumour: a case report 2016
- Effects of cisplatin and letrozole on surgically induced endometriosis and comparison of the two medications in a rat model 2016
- The unexpected conundrum of endometrioid carcinoma in deep rectal endometriosis arising 11 years after total hysterectomy bilateral salpingo-oophorectomy 2015
- Bowel Endometriosis with Hemoperitoneum Complicating Pregnancy 2013
- Transmembrane estrogen receptor GPR30 is more frequently expressed in malignant than benign ovarian endometriotic cysts and correlates with MMP-9 expression 2012
- Molecular links between endometriosis and cancer 2012
- Endometrioid adenocarcinoma in the native ureter of a renal transplant patient: case report and review of the literature 2010
- Adenocarcinoma endometrioide de ovário em parede abdominal 2010
- Endometriosis 2009
- Hormone replacement therapy in women with past history of endometriosis 2006
- Ureteral mullerian carcinosarcoma (mixed mullerian tumor) associated with endometriosis occurring in a patient with a concentrated soy isoflavones supplementation 2006
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- europepmc
- last seen: 2026-10-16T06:09:50.462052+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:03:24.829172+00:00
- unpaywall
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