Endometrioid adenocarcinoma with squamous differentiation arising from ureteral endometriosis in a patient with no history of gonadal endometriosis
article
OA: closed
CC0
⤵ 19 in-corpus citations
AI-generated summary
This case report details an unusual instance of endometrioid adenocarcinoma with squamous differentiation that originated from ureteral endometriosis in a patient without a history of gonadal endometriosis.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
BackgroundMalignant transformation may occur in up to 1% of women with endometriosis and only 20% of these cases occur at extragonadal pelvic sites. Similarly, urinary tract endometriosis is rare and occurs in only 1% of all endometriotic lesions.CaseAn endometrioid carcinoma with squamous differentiation arising from periureteral endometriosis presented as a pelvic mass encasing the right ureter. The patient had a history of total hysterectomy and bilateral salpingo-oopherectomy 8 years earlier because of bilateral serous benign cysts with right hemorrhagic corpus luteum and uterine fibroids, and has since been under unopposed estrogen replacement therapy for 5 years.ConclusionThis is the second case of a malignancy arising in endometriosis presenting as an obstructive ureteral mass and the first case of a patient with this condition whose endometriosis is not consistent with a gonadal origin. An analysis of the case and related literature is presented together with the discussion of possible pathogenetic mechanisms.
My notes (saved in your browser only)
Condition tags
MeSH descriptors
Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
References (10)
- ENDOMETRIAL CARCINOMA OF THE OVARY, ARISING IN ENDOMETRIAL TISSUE IN THAT ORGAN via openalex
- Hyperestrogenism: A Relevant Risk Factor for the Development of Cancer from Endometriosis via openalex
- Left lateral predisposition of endometriosis and endometrioma via openalex
- Malignancy arising in extragonadal endometriosis.A case report and summary of the world literature via openalex
- Malignancy arising in extraovarian endometriosis during estrogen stimulation. via openalex
- Ovarian and extraovarian endometriosis-associated cancer via openalex
- Surgical treatment of ureteral obstruction from endometriosis: our experience with thirteen cases via openalex
- Unilateral hydronephrosis resulting from intraluminal obstruction of the ureter by adenosquamous endometrioid carcinoma arising from disseminated endometriosis via openalex
- W2016891897 via openalex
- W1982582880 via openalex
Cited by (20)
- Case Report: Malignant transformation of deep infiltrating endometriosis: a report of two cases and literature review 2026
- Primary Retroperitoneal Carcinomas: New Insights into Pathogenesis and Clinical Management in Comparison with Ovarian Carcinomas and Carcinoma of Unknown Primary 2023
- Malignant Transformation of Postmenopausal Endometriosis: A Systematic Review of the Literature 2021
- A Rare Case of Combined Endometrioid Adenocarcinoma Arising from Uterine Adenomyosis and Clear Cell Carcinoma Arising from Parametrial Deep Endometriosis 2021
- Malignancies Associated with Extraovarian Endometriosis: A Literature Review 2021
- Endometriosis-associated Extraovarian Malignancies: A Challenging Question for the Clinician and the Pathologist 2020
- ♂♀ Müllerian Lesions of the Bladder: Endometriosis, Endosalpingiosis, Endocervicosis, and Müllerianosis 2019
- Retroperitoneal Endometrioid Carcinoma Arising from Ureteral Endometriosis 2019
- Ureteral endometriosis: a systematic review of epidemiology, pathogenesis, diagnosis, treatment, risk of malignant transformation and fertility 2018
- Post hysterectomy occurrence of endometrial adenocarcinoma in association with granulosa cell tumour: a case report 2016
- Effects of cisplatin and letrozole on surgically induced endometriosis and comparison of the two medications in a rat model 2016
- The unexpected conundrum of endometrioid carcinoma in deep rectal endometriosis arising 11 years after total hysterectomy bilateral salpingo-oophorectomy 2015
- Bowel Endometriosis with Hemoperitoneum Complicating Pregnancy 2013
- Transmembrane Estrogen Receptor GPR30 is More Frequently Expressed in Malignant Than Benign Ovarian Endometriotic Cysts and Correlates With MMP-9 Expression 2012
- Molecular links between endometriosis and cancer 2012
- Endometrioid Adenocarcinoma in the Native Ureter of a Renal Transplant Patient: Case Report and Review of the Literature 2010
- Adenocarcinoma endometrioide de ovário em parede abdominal 2010
- Endometriosis 2009
- Hormone replacement therapy in women with past history of endometriosis 2006
- Ureteral mullerian carcinosarcoma (mixed mullerian tumor) associated with endometriosis occurring in a patient with a concentrated soy isoflavones supplementation 2006
Source provenance
- europepmc
- last seen: 2026-09-19T06:15:14.566301+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:15:29.922408+00:00
- unpaywall
- last seen: 2026-09-18T06:25:56.777850+00:00
License: CC0
· commercial use OK