Nuevos conceptos en la Fisiopatología de la Endometriosis: Inmunología y endocrinología celular

Ana Karen Ramírez Alvarado, Carlos Escalante Gómez
In: Revista Médica de Costa Rica y Centroamérica · 2014 · vol. 71(611) , pp. 455–461 · W4936818
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Abstract

Endometriosis is a benign chronic inflammatory disease characterized by the presence of endometrial tissue outside the uterine cavity, typically within the pelvis. Since initial descriptions of the disease, several theories have been proposed to explain the genesis of endometriosis; however none can adequately expound the pathophysiology of the disease. Because of that reason, recent studies on endometriosis have focused on immunological and endocrinological events that are part of the pathophysiology of endometriosis. Studies have found that the abnormal immune response of women with endometriosis is mainly characterized by an imbalance between the action of M1 and M2 type macrophages and such imbalance triggers a series of events that culminate in the development of the disease.

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endometriosis

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