Ileal Endometriosis Masquerading as Crohn's Ileitis

Boulton R, R Boulton, Ralph Boulton, M H Chawla, Chawla MH, Mukesh H. Chawla, S Poole, Poole S, Simon Poole, H J Hodgson, H. J. F. Hodgson, Hodgson HJ, Barrison IG, I G Barrison
Journal of clinical gastroenterology · 1997 · vol. 25(1) , pp. 338–342 · doi:10.1097/00004836-199707000-00009 · PMID:9412916 · W1967741776
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-09 ⓘ

Ileal endometriosis can mimic Crohn's disease of the ileum, presenting with fibrosis and strictures that necessitate its consideration in differential diagnoses, even with existing Crohn's disease.

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⚙ AI-generated deep summary by qwen3.7-flash, 2026-08-18 · read from full text ⓘ

This case report describes two female patients, one of whom had a history of Crohn's colitis, who presented with ileal obstruction caused by endometriosis. The authors highlight that deep infiltrating endometriosis in the distal ileum can cause fibrosis and strictures that closely mimic the clinical and radiological features of Crohn's disease. They emphasize that clinicians must consider endometriosis in the differential diagnosis for ileal lesions, even when other sites of Crohn's disease are already established in the gastrointestinal tract. This paper is centrally about endometriosis — specifically its rare presentation as ileal disease mimicking Crohn's ileitis.

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Abstract

Endometriosis is usually confined to the pelvis but may involve distant organs. When the small bowel is affected, endometriosis has a propensity to develop in the distal ileum, which may lead to fibrosis and stricture formation that can be confused with Crohn's disease. Here were describe two women, one with antecedent Crohn's colitis in whom ileal endometriosis mimicked obstructing Crohn's disease of the terminal ileum. These reports illustrate that ileal endometriosis must be considered in the differential diagnosis of Crohn's disease of the ileum, even in the presence of Crohn's disease elsewhere in the gastrointestinal tract.
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Clinical Studies Ileal Endometriosis Masquerading as Crohn's Ileitis - Ralph Boulton - Mukesh H. Chawla - Simon Poole - Humphrey J. F. Hodgson - Ian G. Barrison Journal of Clinical Gastroenterology 25(1):p 338-342, July 1997. Endometriosis is usually confined to the pelvis but may involve distant organs. When the small bowel is affected, endometriosis has a propensity to develop in the distal ileum, which may lead to fibrosis and stricture formation that can be confused with Crohn's disease. Here we describe two women, one with antecedent Crohn's colitis in whom ileal endometriosis mimicked obstructing Crohn's disease of the terminal ileum. These reports illustrate that ileal endometriosis must be considered in the differential diagnosis of Crohn's disease of the ileum, even in the presence of Crohn's disease elsewhere in the gastrointestinal tract. Copyright © Lippincott-Raven Publishers

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Condition tags

endometriosis

MeSH descriptors

Crohn Disease Endometriosis Ileal Diseases Adult Biopsy Crohn Disease Crohn Disease Diagnosis, Differential Endometriosis Endometriosis Female Humans Ileal Diseases Ileal Diseases Ileitis Ileitis Ileitis

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