Danazol-induced cholestasis
Case report
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⤵ 5 in-corpus citations
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This case report describes a patient who developed panlobular cholestasis with inflammation after high-dose Danazol treatment, which resolved upon drug discontinuation.
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Abstract
A 39-yr-old female on high-dose Danazol presented with jaundice and pruritus. Danazol-induced cholestasis was suspected, and the drug was discontinued. A liver biopsy revealed panlobular cholestasis with portal and periportal inflammation. The cholestasis resolved completely in 8 wk. This is a rare case of Danazol-induced cholestasis and should be considered in the differential diagnosis of drug-induced liver injury.
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Cited by (5)
- Danazol induced acute icteric cholestatic hepatitis 2007
- BILE DUCT HAMARTOMA OCCURRING IN ASSOCIATION WITH LONG‐TERM TREATMENT WITH DANAZOL 1997
- Ultrastructural features of danazol-induced cholestasis: a case study 1996
- Liver Damage Induced by Danazol 1994
- Resolution of danazol-induced cholestasis with S-adenosylmethionine 1993
Source provenance
- europepmc
- last seen: 2026-10-11T09:27:45.537177+00:00
- openalex
- last seen: 2026-05-11T04:02:40.442879+00:00
- pubmed
- last seen: 2026-10-08T21:21:08.819620+00:00
License: CC0
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