Predictive value of magnetic resonance imaging in differentiating between leiomyoma and adenomyosis.

Rosa Moghadam, Ruth B Lathi, Babac Shahmohamady, Naghmeh S Saberi, N. Saberi, Ceana Nezhat, Ceana H Nezhat, Farr Nezhat, Camran Nezhat
JSLS : Journal of the Society of Laparoendoscopic Surgeons · 2007 · vol. 10(2) , pp. 216–9 · PMID:16882423 · PMC3016115 · W2400329334
article OA: gold CC0 ⤵ 21 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study evaluated MRI's preoperative diagnostic accuracy, finding high sensitivity and low specificity for leiomyoma, and high specificity and low sensitivity for adenomyosis, suggesting its use as an adjunctive tool.

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Abstract

OBJECTIVE: We evaluated the role of MRI as a preoperative diagnostic tool for leiomyoma and adenomyosis. METHOD: This is a retrospective chart review at a university-based hospital. The study included 1517 women who underwent hysterectomy or myomectomy over a 5-year period, and 153 women with a preoperative pelvic MRI were included. Comparisons were made between the results of the MRI and postoperative pathology reports. RESULTS: The MRI and pathology report were the same for 136 of 144 women with leiomyoma and 12 of 31 women with adenomyosis. The MRI had 94% sensitivity and 33% specificity for leiomyoma and 38% sensitivity and 91% specificity for adenomyosis. Positive and negative predictive values of MRI for leiomyoma were 95% and 27% with 90% accuracy. Positive and negative predictive values of MRI for adenomyosis were 52% and 85%, respectively, with 80% accuracy. CONCLUSION: MRI has a high sensitivity and a low specificity for diagnosing leiomyoma and a high specificity and a low sensitivity for diagnosing adenomyosis. Due to the high cost and technical variations, we suggest using MRI only as an adjunctive diagnostic tool when ultrasound is not conclusive and differentiation between the 2 pathologies ultimately affects patient management.

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Condition tags

endometriosisadenomyosis

MeSH descriptors

Endometriosis Leiomyoma Magnetic Resonance Imaging Uterine Diseases Uterine Neoplasms Adult Aged Diagnosis, Differential Endometriosis Female Humans Leiomyoma Middle Aged Predictive Value of Tests Retrospective Studies Uterine Diseases Uterine Neoplasms

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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