Clinical and ultrasonological features of adenomyosis and its histopathological correlation

In: International Journal of Reproduction, Contraception, Obstetrics and Gynecology · 2016 · pp. 3283–3289 · doi:10.18203/2320-1770.ijrcog20163158 · W2520627411
article OA: diamond CC0 ⤵ 5 in-corpus citations
AI-generated summary by gemini-2.5-flash-lite, 2026-06-07

This study found that transvaginal sonography, particularly endomyometrial junction blurring, accurately diagnosed adenomyosis in patients with heavy menstrual bleeding and dysmenorrhea.

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AI-generated deep summary by claude@2026-06, 2026-06-07 · read from full text

This study evaluated the clinical and transvaginal ultrasound (TVS) features of adenomyosis in 78 menstruating women presenting with heavy menstrual bleeding, dysparenuia, dysmenorrhea, and/or chronic pelvic pain, comparing TVS findings (myometrial echo texture, myometrial cysts, and endomyometrial junction blurring) with post-hysterectomy histopathology. In histopathology-positive cases, heavy menstrual bleeding was reported in 97.8% and dysmenorrhea in 93.48%, and TVS showed sensitivity of 89.13% and specificity of 90.62% (diagnostic accuracy 89.74%). The authors conclude that TVS can diagnose adenomyosis without additional diagnostic tools and that endomyometrial junction blurring is the most sensitive and specific TVS criterion. Limitations are not explicitly detailed in the provided text. This paper is centrally about endometriosis and adenomyosis — it focuses on adenomyosis clinical and ultrasonographic features correlated with histopathology.

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Abstract

Background: Adenomyosis is a common gynaecological condition that affects the menstruating women. Uterine enlargement, dysmenorrhoea and HMB are regarded as the cardinal clinical symptoms of adenomyosis. Classically it was thought, compared with ultrasonography, when adenomyosis is suspected, MRI enables more accurate diagnosis of the disease.Methods: 78 subjects were enrolled after an informed consent that had complaints of HMB, Dysparenuia, dysmenorrhea, and chronic pelvic pain. Detailed history of the enrolled subjects was taken, followed by a clinical examination. These patients were then subjected to TVS where myometrial echo texture, presence of myometrial cysts, blurring of endomyometrial junction was noted. After hysterectomy, histopathological diagnosis was obtained.Results: 78 subjects enrolled in the study. The mean age was 44.2 years. 43.5% had parity of 4 or more. HMB was present in 97.8% and dysmenorrhea in 93.48 % of HPE positive patient. Transvaginal sonography had a sensitivity of 89.13%, specificity of 90.62%, positive likelihood ratio of 9.51, negative likelihood ratio of 0.12, positive predictive value of 93.18%, negative predictive value of 85.29% and a diagnostic accuracy of 89.74%.Conclusions: Thus adenomyosis has a prevalence of 30.23%. HMB with dysmenorrhoea and chronic pelvic pain helps in diagnosis. TVS is both sensitive and specific in diagnosing adenomyosis without need for additional diagnostic tool. Endomyometrial junction blurring is the sensitive and specific criteria on TVS.
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Background

Adenomyosis is a common gynaecological condition that affects the menstruating women. Uterine enlargement, dysmenorrhoea and HMB are regarded as the cardinal clinical symptoms of adenomyosis. Classically it was thought, compared with ultrasonography, when adenomyosis is suspected, MRI enables more accurate diagnosis of the disease.

Methods

78 subjects were enrolled after an informed consent that had complaints of HMB, Dysparenuia, dysmenorrhea, and chronic pelvic pain. Detailed history of the enrolled subjects was taken, followed by a clinical examination. These patients were then subjected to TVS where myometrial echo texture, presence of myometrial cysts, blurring of endomyometrial junction was noted. After hysterectomy, histopathological diagnosis was obtained.

Results

78 subjects enrolled in the study. The mean age was 44.2 years. 43.5% had parity of 4 or more. HMB was present in 97.8% and dysmenorrhea in 93.48 % of HPE positive patient. Transvaginal sonography had a sensitivity of 89.13%, specificity of 90.62%, positive likelihood ratio of 9.51, negative likelihood ratio of 0.12, positive predictive value of 93.18%, negative predictive value of 85.29% and a diagnostic accuracy of 89.74%.

Conclusions

Thus adenomyosis has a prevalence of 30.23%. HMB with dysmenorrhoea and chronic pelvic pain helps in diagnosis. TVS is both sensitive and specific in diagnosing adenomyosis without need for additional diagnostic tool. Endomyometrial junction blurring is the sensitive and specific criteria on TVS. Metrics

References

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adenomyosischronic_pelvic_paindysmenorrhea

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