Endometriosis-associated ovarian cancer occurs early during follow-up of endometrial cysts

Kosuke Murakami, Yasushi Kotani, Reona Shiro, Hisamitsu Takaya, Hidekatsu Nakai, Noriomi Matsumura
International journal of clinical oncology · 2019 · vol. 25(1) , pp. 51–58 · doi:10.1007/s10147-019-01536-5 · PMID:31473885 · W2970849246
review OA: closed CC0 ⤵ 28 in-corpus citations
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

Reviewing 79 cases, this study found endometriosis-associated ovarian cancer develops within a median of 36 months after endometrial cyst diagnosis.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This paper examined reported endometriosis-associated ovarian cancer (EAOC) cases thought to arise from ovarian endometrial cysts by searching PubMed, Web of Science, and Ichushi-Web for publications since January 2000, then calculating the interval from cyst follow-up onset to ovarian cancer diagnosis. Across 79 cases from 32 articles, the median time from endometrial cyst diagnosis to ovarian cancer diagnosis was 36 months, with about 75% diagnosed within 60 months and most within 120 months. The authors note the study is based on published case reports/series and therefore may be influenced by selection and reporting biases, limiting inference about true natural history. This paper is centrally about endometriosis — it focuses on endometriosis-associated ovarian cancer arising early during follow-up of endometrial (endometriotic) ovarian cysts.

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Condition tags

endometriosis

MeSH descriptors

Carcinoma, Endometrioid Carcinoma, Ovarian Epithelial Endometriosis Ovarian Cysts Ovarian Neoplasms Adult Carcinoma, Endometrioid Carcinoma, Endometrioid Carcinoma, Endometrioid Carcinoma, Ovarian Epithelial Carcinoma, Ovarian Epithelial Carcinoma, Ovarian Epithelial Endometriosis Endometriosis Endometriosis Female Follow-Up Studies Humans Middle Aged Ovarian Cysts

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (28)

Cited by (28)

Source provenance

europepmc
last seen: 2026-06-11T06:19:48.454388+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:22:35.348889+00:00
License: CC0 · commercial use OK