Early Detection of Ovarian Clear Cell Carcinoma in a Postmenopausal Patient Using Sonography: A Case Report

Delaney Kennedy
In: Journal of Diagnostic Medical Sonography · 2026 · doi:10.1177/87564793261428422 · W7161045526
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Sonography detected stage IC3 ovarian clear cell carcinoma in a postmenopausal patient without typical risk factors, revealing a cystic mass with vascularized nodules that prompted further investigation and diagnosis.

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Abstract

Ovarian clear cell carcinoma (OCCC) represents an uncommon and aggressive form of epithelial ovarian cancer, often diagnosed, due to its relation to endometriosis. This case report is centered on a 63-year-old postmenopausal patient with no history of endometriosis or pertinent risk factors but diagnosed with stage IC3 ovarian clear cell carcinoma. It was initially identified through transabdominal and transvaginal sonography. Sonographic findings of a large cystic pelvic mass with internal vascularized solid nodules led to further imaging and surgical intervention. Histopathology confirmed OCCC coinciding with intraoperative rupture and malignant peritoneal washings. This case emphasizes the pivotal role of sonography in detecting suspicious adnexal masses, particularly when biomarkers like CA-125 are only slightly elevated. Early and accurate diagnostic imaging is crucial for prompt diagnosis and treatment, especially given OCCC’s poor response to chemotherapy, at more advanced stages.
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endometriosis

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last seen: 2026-07-31T06:01:29.331002+00:00
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