Potential clinical applications of uterine artery occlusion

Andrea S. Lukes, H. Fernandez, Olav Istre, Peter Oppelt
In: Expert Review of Obstetrics & Gynecology · 2009 · vol. 4(5) , pp. 533–546 · doi:10.1586/eog.09.36 · W2065126607
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-08 ⓘ

Doppler-guided uterine artery occlusion shows promise for treating uterine fibroid symptoms and may be applicable to adenomyosis, postpartum hemorrhage, ectopic pregnancy, gestational trophoblastic neoplasia, and abnormal uterine bleeding.

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Abstract

Leiomyomata uteri remain a common gynecologic problem, associated with a significant clinical and economic burden of illness. Despite a variety of currently available interventions for uterine fibroids, there remains an unmet clinical need for novel therapies. Doppler-guided uterine artery occlusion is a promising investigational procedure for the treatment of symptoms associated with uterine fibroids. This procedure may also have potential uses in the management of adenomyosis, postpartum hemorrhage, ectopic pregnancy, gestational trophoblastic neoplasia and heavy abnormal uterine bleeding in women with bleeding disorders, and as neoadjuvant therapy in conjunction with myomectomy. A teleconference of leading gynecologic surgeons was held to build consensus around potential uses of this new technology. Based on pilot studies and expert opinion, Doppler-guided uterine artery occlusion appears to have promise for the management of fibroid-associated symptoms and may have application in the setting of other obstetric and gynecologic disorders.

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Condition tags

adenomyosis

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (100)

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