H. Fernandez

BACKGROUND: Diagnosis of endometriosis is a challenge. The recent development of a saliva-based micro-ribonucleic acid (miRNA) signature for the diagnosis of endometriosis may enable a timelier and less invasive approach, but this requires …

Endometriosis is a complex gynecologic disorder characterized primarily by symptoms of pelvic pain, infertility, and altered quality of life. National and international guidelines highlight the diagnostic difficulties and lack of conclusive…

STUDY QUESTION: Is increasing the intensity of high-intensity focused ultrasound (HIFU) by 30% in the treatment of rectal endometriosis a safe procedure? SUMMARY ANSWER: This study demonstrates the safety of a 30% increase in the intensity…

The French National College of Obstetricians and Gynecologists (CNGOF) published guidelines for managing endometriosis-associated pain in 2018. Given the development of new pharmacological therapies and a review that was published in 2021, …

BACKGROUND: The discovery of a saliva-based micro–ribonucleic acid (miRNA) signature for endometriosis in 2022 opened up new perspectives for early and noninvasive diagnosis of the disease. The 109-miRNA saliva signature is the product of m…

Study objectiveTo evaluate the epidemiologic and economic burden related to adhesions and their complications for the French healthcare system.DesignA descriptive and economic retrospective analysis.SettingMedicalized information system pro…

ObjectiveTo evaluate the effect of a 10 mg per day 12 week treatment of ulipristal acetate (UPA) on abnormal uterine bleeding due to adenomyosis.DesignA double-blind phase 2 randomized controlled pilot study.SettingFrom May 2015 to February…

First-line diagnostic investigations for endometriosis are physical examination and pelvic ultrasound. The second-line investigations are: targeted pelvic examination performed by an expert clinician, transvaginal ultrasound performed by an…

OBJECTIVE: The objective of this work is to evaluate the place of new treatments in the management of endometriosis outside the context of infertility. METHODS: A review of the literature was conducted by consulting Medline data until July…

First-line investigations to diagnose endometriosis are clinical examination and pelvic ultrasound. Second-line investigations include pelvic examination performed by a referent clinician, transvaginal ultrasound performed by a referent ech…

ObjectiveTo analyse the literature on the treatment of adolescent painful endometriosis.MethodThis work is based on a Review of the literature between January 2006 and December 2017. The Medline (Pubmed) and Cochrane database were searched …

ObjectiveTo provide clinical practice guidelines for the management of painful endometriosis in women without infertility.MethodsSystematic review of the literature literature since 2006, level of evidence rating, external proofreading and …

The available literature, from 2006 to 2017, on hormonal treatment has been analysed as a contribution to the HAS-CNGOF task force for the treatment of endometriosis. Available data are heterogeneous and the general level of evidence is mod…

ObjectiveTo evaluate the conservative surgical treatment for abnormal uterine bleeding from the Medicalized Information System Program (PMSI).Materials and methodsThe diagnosis codes were selected from 10th version of the international clas…