The effect of the levonorgestrel-releasing intrauterine system, Mirena® on mast cell numbers in women with endometriosis undergoing symptomatic treatment

Samuel Engemise; Samuel L Engemise; Jonathon M Willets; J.O. Emembolu; Joseph O Emembolu; Justin C Konje

doi:10.1016/j.ejogrb.2011.09.007

The effect of the levonorgestrel-releasing intrauterine system, Mirena® on mast cell numbers in women with endometriosis undergoing symptomatic treatment

Samuel Engemise, Samuel L Engemise, Jonathon M Willets, J.O. Emembolu, Joseph O Emembolu, Justin C Konje

European journal of obstetrics, gynecology, and reproductive biology · 2011 · vol. 159(2) , pp. 439–442 · doi:10.1016/j.ejogrb.2011.09.007 · PMID:22018831 · W2081097805

article OA: closed CC0 ⤵ 7 in-corpus citations

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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This study investigated the impact of the levonorgestrel-releasing intrauterine system (Mirena®) on mast cell counts in women with endometriosis experiencing symptomatic relief.

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Contraceptive Agents, Female Endometriosis Endometriosis Intrauterine Devices, Medicated Levonorgestrel Mast Cells Adolescent Adult Biopsy Cell Count Contraceptive Agents, Female Contraceptive Agents, Female Endometriosis Endometriosis Endometriosis Endometrium Endometrium Endometrium Endometrium Endometrium

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References (25)

Changes in glandular and stromal estrogen and progesterone receptor isoform expression in eutopic and ectopic endometrium following treatment with the levonorgestrel-releasing intrauterine system via openalex
Cyclooxygenase-2 expression in deep endometriosis and matched eutopic endometrium via openalex
Cytokine profiles in serum and peritoneal fluid from infertile women with and without endometriosis via openalex
EPIDEMIOLOGY OF ENDOMETRIOSIS via openalex
Epigallocatechin-3-gallate inhibits estrogen-induced activation of endometrial cells in vitro and causes regression of endometriotic lesions in vivo via openalex
Immunobiology of endometriosis via openalex
Increased Mast Cell Density in Peritoneal Endometriosis Compared with Eutopic Endometrium with Endometriosis via openalex
Increase of Activated Mast Cells in Human Endometriosis via openalex
Peritoneal Vascular Density Assessment Using Narrow-Band Imaging and Vascular Analysis Software, and Cytokine Analysis in Women With and Without Endometriosis via openalex
Stem Cell Factor (SCF) Concentrations in Peritoneal Fluid of Women with or without Endometriosis via openalex
The efficacy, side-effects and continuation rates in women with symptomatic endometriosis undergoing treatment with an intra-uterine administered progestogen (levonorgestrel): a 3 year follow-up via openalex
The evaluation of the effectiveness of an intrauterine-administered progestogen (levonorgestrel) in the symptomatic treatment of endometriosis and in the staging of the disease via openalex
Treating endometriosis as an autoimmune disease via openalex
W2115835613 via openalex
W2010606095 via openalex
W2123134517 via openalex
W2141369001 via openalex
W2053998452 via openalex
W2053305404 via openalex
W2042810511 via openalex
W2038480158 via openalex
W2033247060 via openalex
W2170487877 via openalex
W2345696364 via openalex
W2468902048 via openalex

Cited by (7)

Source provenance

europepmc: last seen: 2026-06-04T01:30:01.192114+00:00
openalex: last seen: 2026-06-10T17:14:06.276822+00:00
pubmed: last seen: 2026-05-13T22:16:29.858026+00:00

License: CC0 · commercial use OK

[1] Changes in glandular and stromal estrogen and progesterone receptor isoform expression in eutopic and ectopic endometrium following treatment with the levonorgestrel-releasing intrauterine system via openalex

[2] Cyclooxygenase-2 expression in deep endometriosis and matched eutopic endometrium via openalex

[3] Cytokine profiles in serum and peritoneal fluid from infertile women with and without endometriosis via openalex

[4] EPIDEMIOLOGY OF ENDOMETRIOSIS via openalex

[5] Epigallocatechin-3-gallate inhibits estrogen-induced activation of endometrial cells in vitro and causes regression of endometriotic lesions in vivo via openalex

[6] Immunobiology of endometriosis via openalex

[7] Increased Mast Cell Density in Peritoneal Endometriosis Compared with Eutopic Endometrium with Endometriosis via openalex

[8] Increase of Activated Mast Cells in Human Endometriosis via openalex

[9] Peritoneal Vascular Density Assessment Using Narrow-Band Imaging and Vascular Analysis Software, and Cytokine Analysis in Women With and Without Endometriosis via openalex

[10] Stem Cell Factor (SCF) Concentrations in Peritoneal Fluid of Women with or without Endometriosis via openalex

[11] The efficacy, side-effects and continuation rates in women with symptomatic endometriosis undergoing treatment with an intra-uterine administered progestogen (levonorgestrel): a 3 year follow-up via openalex

[12] The evaluation of the effectiveness of an intrauterine-administered progestogen (levonorgestrel) in the symptomatic treatment of endometriosis and in the staging of the disease via openalex

[13] Treating endometriosis as an autoimmune disease via openalex

[14] W2115835613 via openalex

[15] W2010606095 via openalex

[16] W2123134517 via openalex

[17] W2141369001 via openalex

[18] W2053998452 via openalex

[19] W2053305404 via openalex

[20] W2042810511 via openalex

[21] W2038480158 via openalex

[22] W2033247060 via openalex

[23] W2170487877 via openalex

[24] W2345696364 via openalex

[25] W2468902048 via openalex