[Endometriosis as a risk factor for ovarian cancer]

Vargas-Hernández VM, Víctor Manuel Vargas-Hernández
Cirugia y cirujanos · 2013 · vol. 81(2) , pp. 163–8 · PMID:23522320 · W1599079350
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Endometriosis is a known risk factor for clear cell and low-grade endometrioid ovarian cancers, but its role in other subtypes remains unclear, necessitating further research into malignant transformation mechanisms.

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Abstract

A history of endometriosis is a risk factor for some subtypes of epithelial ovarian cancer. Endometriosis is associated with increased risk of ovarian clear cell, serous low-grade endometrioid cancer, but it is unclear what the role of endometriosis is in the development of other histopathological subtypes of ovarian cancer, such as high-grade serous borderline tumors subtypes or borderline serous and mucinous cancers. An understanding of the mechanisms leading to malignant transformation of endometriosis will be needed to identify subgroups of women at increased risk of ovarian cancer. This is important because of their high prevalence and cause of infertility in Mexico and the world. All factors must be considered during the decision-making process for the treatment of endometriosis, including the rare malignant transformation.

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Condition tags

endometriosisinfertility

MeSH descriptors

Endometriosis Ovarian Neoplasms Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Mucinous Adenocarcinoma, Mucinous Adenocarcinoma, Mucinous Carcinoma, Endometrioid Carcinoma, Endometrioid Carcinoma, Endometrioid Comorbidity Comorbidity Cystadenocarcinoma, Serous Cystadenocarcinoma, Serous Cystadenocarcinoma, Serous Cystadenocarcinoma, Serous Endometriosis Endometriosis Female

Citation neighborhood (2-hop)

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References (30)

Cited by (6)

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