Coexistence of cervical endometriosis with premalignant and malignant gynecological pathologies: report on a series of 27 cases

Michail Matalliotakis, Charoula Matalliotaki, Maria I. Zervou, Konstantinos Krithinakis, Krithinakis K, Ioannis Kalogiannidis, Kalogiannidis I, Goulielmos GN, George N. Goulielmos
Women & health · 2021 · vol. 61(9) , pp. 896–901 · doi:10.1080/03630242.2021.1991073 · PMID:34696701 · W3210621347
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This study of 27 cervical endometriosis cases found a high coexistence with premalignant cervical intraepithelial neoplasia (70%) and a notable prevalence of human papilloma virus and gynecological cancers.

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Abstract

Although cervical endometriosis represents a rare condition, there is evidence that implicates a complex interaction with other gynecological pathologies. This study aims to highlight this entity and further to explore the impact of oncological pathology of female genital tract on patients with cervical endometriosis. We retrospectively investigated the medical and pathological reports of 27 cases with cervical endometriosis, which were diagnosed by tissue biopsy. The results of the study show a relationship between CIN (cervical intraepithelial neoplasia) cases 19/27 (70percent) and cervical endometriosis. CIN I was more frequently found compared to patients with CIN II and CIN III. Furthermore, a high prevalence of HPV (human papilloma virus) was confirmed. Out of 27 patients, 2 cases with cervical (7.4percent), 2 with endometrial (7.4percent) and 3 with ovarian cancer (11.1percent) were detected. We confirmed the coexistence of more than one malignant gynecological pathology with cervical endometriosis in four cases (14.8percent). To conclude, cervical endometriosis is a rare disease co-existing considerably with premalignant and malignant gynecological conditions according to our data. Although the pathophysiology and genetics of cervical dysplasia is well delineated, further research is needed to establish the association between cervical endometriosis and gynecological premalignant and malignant pathology.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Papillomavirus Infections Papillomavirus Infections Uterine Cervical Dysplasia Uterine Cervical Dysplasia Uterine Cervical Dysplasia Uterine Cervical Dysplasia Uterine Cervical Neoplasms Uterine Cervical Neoplasms Female Female Humans Humans Retrospective Studies Retrospective Studies

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (25)

Cited by (5)

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