Adenomyosis in the Broad Ligament and Tamoxifen: Report of a Case
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Abstract
Adenomyosis confined to the broad ligament is extremely rare. Herein we present a case of adenomyosis in the broad ligament with unusual gross features. This 41-year-old woman had been on tamoxifen therapy for 3 years due to breast cancer. Ten months after discontinuing tamoxifen, she underwent exploratory laparotomy for a right adnexal mass suspected as ovarian malignancy. At laparotomy, the mass was located in the right broad ligament with a fibrous stalk connecting to the uterus. Total abdominal hysterectomy with bilateral salpingo-oophorectomy was performed. Histopathologic examination revealed adenomyosis with cyst formation and an unusual thick capsule. The possible effects of tamoxifen upon the uterus are discussed in this article, in view of reports of tamoxifen associated with endometrial carcinoma and endometriosis.
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Cited by (7)
- Broad Ligament Endometriosis Presenting as a Solid Mass: A Diagnostic “Curveball” 2018
- Endometrioma contained within the broad ligament 2014
- Adenomiosis: una afección uterina frecuente 2006
- Large cystic uterine adenomyoma showing marked epithelial metaplasia and exophytic polypoid growth 2003
- Peritoneal endometriosis in the broad ligament presenting as a large tumor 2002
- Exacerbation of endometriosis as a result of premenopausal tamoxifen exposure 2000
- Surgical and medical treatment of adenomyosis 1998
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- europepmc
- last seen: 2026-06-04T01:30:01.192114+00:00
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- pubmed
- last seen: 2026-05-13T22:10:52.568893+00:00
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