Additional file 7 of The IL-33-ST2 axis plays a vital role in endometriosis via promoting epithelial–mesenchymal transition by phosphorylating β-catenin

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This study investigated the autocrine effect of IL-33 on stromal cells, finding it influences α-SMA expression, cell viability, and migration in eutopic and ectopic endometrial cells from endometriosis patients.

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Abstract

Additional file 7: Supplementary Figure 3. Autocrine Effect of IL-33 on Stromal Cells. A-C. mRNA (A) and protein (B, C) expression of α-SMA in eutopic ESCs and ectopic ESCs treated with IL-33 or TGF-β1. D-F Cell viability (D) and migration (E, F) of eutopic ESC and ectopic ESC treated with IL-33. Ctrl-EU, eutopic endometrium of controls; EMs-EU, eutopic endometrium of patients with endometriosis; EMs-EC, ectopic lesions. Data are presented as mean ± SEM. All data were analyzed using one-way ANOVA followed by Dunnett’s post hoc test and Student’s t-test; * p < 0.05, ** p < 0.01, *** p < 0.001.

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Condition tags

endometriosis

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (60)

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openalex
last seen: 2026-05-13T20:12:55.465734+00:00
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