Malignant mixed mullerian tumor arising in extragenital endometriosis: Report of a case and review of the literature

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This case report describes a malignant mixed mullerian tumor that arose in extragenital endometriosis and reviews relevant literature on this rare occurrence.

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Abstract

A primary malignant mixed Mullerian tumor (MMMT) was found in the wall of the rectum of a 67-year-old female. The uterus, fallopian tubes, and ovaries had been previously excised for benign disease. The tumor was associated with foci of benign endometriosis. A literature review of extragenital MMMTs indicates that these are extremely rare tumors. This case supports the theory that endometriosis may serve as a progenitor to extraendometrial malignancy.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Neoplasms, Germ Cell and Embryonal Rectal Neoplasms Aged Endometriosis Female Humans Neoplasm Recurrence, Local Neoplasm Recurrence, Local Neoplasms, Germ Cell and Embryonal Rectal Neoplasms

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (18)

Cited by (16)

Source provenance

europepmc
last seen: 2026-07-26T06:08:39.051465+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:09:40.384591+00:00
License: CC0 · commercial use OK