Metformin regulates stromal-epithelial cells communication via Wnt2/β-catenin signaling in endometriosis
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Metformin regulates stromal-epithelial cell communication in endometriosis by modulating Wnt2/β-catenin signaling.
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References (20)
- Endometriotic stromal cells lose the ability to regulate cell-survival signaling in endometrial epithelial cells in vitro via openalex
- Impaired Down-Regulation of E-Cadherin and β-Catenin Protein Expression in Endometrial Epithelial Cells in the Mid-Secretory Endometrium of Infertile Patients with Endometriosis via openalex
- Metformin inhibits growth of eutopic stromal cells from adenomyotic endometrium via AMPK activation and subsequent inhibition of AKT phosphorylation: a possible role in the treatment of adenomyosis via openalex
- Metformin regresses endometriotic implants in rats by improving implant levels of superoxide dismutase, vascular endothelial growth factor, tissue inhibitor of metalloproteinase-2, and matrix metalloproteinase-9 via openalex
- Transcriptional Characterizations of Differences between Eutopic and Ectopic Endometrium via openalex
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Cited by (17)
- Identification of FZD7 as a potential ferroptosis-related diagnostic gene in endometriosis by bioinformatics analysis 2025
- Effect of cabergoline and metformin combination therapy in the treatment of infertile women with symptomatic endometrioma: comparison with cabergoline alone 2025
- Decoding adenomyosis pathogenesis using an assembloid model 2025
- Identification and validation of risk score model based on gene set activity as a diagnostic biomarker for endometriosis 2023
- Effects of metformin and ganirelix on subcutaneous endometriosis in a mouse model of autophagy-related cell death 2023
- Research advances in endometriosis-related signaling pathways: A review 2023
- Advances in Metformin for Treatment of En-dometriosis 2023
- Metformin Alleviates Endometriosis and Potentiates Endometrial Receptivity via Decreasing VEGF and MMP9 and Increasing Leukemia Inhibitor Factor and HOXA10 2022
- Metformin as a Potential Treatment Option for Endometriosis 2022
- The latest advances in the pharmacological management of endometriosis 2022
- Endometrial stromal cell proteomic analysis reveals LIM and SH3 protein 1 (LASP1) plays important roles in the progression of adenomyosis 2021
- Pharmaceuticals targeting signaling pathways of endometriosis as potential new medical treatment: A review 2021
- Changing prostaglandin E2 (PGE<sub>2</sub>) signaling during lesional progression and exacerbation of endometriosis by inhibition of PGE<sub>2</sub> receptor EP2 and EP4 2021
- Oestrogen, progesterone and stem cells: the discordant trio in endometriosis? 2018
- Epithelial-to-mesenchymal transition in the development of endometriosis 2017
- microRNA expression analysis in endometriotic serum treated mesenchymal stem cells 2017
- Pharmacological treatment of endometriosis: review of current and new options for treatment 2016
Source provenance
- europepmc
- last seen: 2026-06-18T06:15:08.409253+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:17:46.044120+00:00
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