Leptin in Obstetrics and Gynecology:

J C Sabogal, Juan Carlos Sabogal, Sabogal JC, L Muñoz, Muñoz L
Obstetrical & gynecological survey · 2001 · vol. 56(4) , pp. 225–230 · doi:10.1097/00006254-200104000-00023 · PMID:11285435 · W2334716580
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This review examines leptin's roles in various gynecologic and obstetrical conditions, including puberty, PCOS, endometriosis, fertility, menopause, and pregnancy complications.

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⚙ AI-generated deep summary by qwen3.7-flash, 2026-09-06 · read from full text ⓘ

This review article examines the physiological role of leptin, a type-1 cytokine involved in cellular maturation and growth, within the contexts of obstetrics and gynecology. The authors analyzed literature from the past six years to discuss how leptin interacts with conditions such as obesity, polycystic ovary syndrome, and pregnancy-induced hypertension. The paper also explores leptin's influence on fetal physiology, puberty, and menopause, providing an overview for clinicians regarding these endocrine relationships. Relevance to endometriosis: listed as one of the gynecologic diseases discussed alongside leptin, though the paper's main focus is a broad review of obstetrical and gynecological applications.

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Abstract

Leptin, a recently described type-1 cytokine, is involved in cellular maturation and growth and appears to have a relationship to some obstetrical and gynecologic diseases. The MEDLINE database was accessed, and leptin-related articles published during the past 6 years were reviewed for their relevance to gynecologic and obstetrical diseases. The relationships between this cytokine and obesity, puberty, polycystic ovary syndrome, endometriosis, assisted fertility, and menopause are discussed. The role of leptin in fetal physiology and in normal and abnormal fetal growth as well as its role in diabetes, pregnancy, and pregnancy-induced hypertension are reviewed. Target Audience: Obstetricians & Gynecologists, Family Physicians Learning Objectives: After completion of this article, the reader will be able to describe leptin physiology, to outline the various relationships between leptin and the endocrine system, and to explain leptin physiology during pregnancy.
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Leptin in Obstetrics and Gynecology: A Review - Juan Carlos Sabogal - Liliana Muñoz Leptin, a recently described type-1 cytokine, is involved in cellular maturation and growth and appears to have a relationship to some obstetrical and gynecologic diseases. The MEDLINE database was accessed, and leptin-related articles published during the past 6 years were reviewed for their relevance to gynecologic and obstetrical diseases. The relationships between this cytokine and obesity, puberty, polycystic ovary syndrome, endometriosis, assisted fertility, and menopause are discussed. The role of leptin in fetal physiology and in normal and abnormal fetal growth as well as its role in diabetes, pregnancy, and pregnancy-induced hypertension are reviewed. Target Audience: Obstetricians & Gynecologists, Family Physicians Learning Objectives: After completion of this article, the reader will be able to describe leptin physiology, to outline the various relationships between leptin and the endocrine system, and to explain leptin physiology during pregnancy.

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Condition tags

endometriosis

MeSH descriptors

Gynecology Leptin Leptin Obstetrics Endocrine System Endocrine System Female Humans Leptin Pregnancy

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (100)

Cited by (5)

Source provenance

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License: CC0 · commercial use OK