Fine Needle Cytology of Endometriosis

Fulciniti F, Franco Fulciniti, Caleo A, Alessia Caleo, Lepore M, Maria Lepore, Adriana Fortunato, Fortunato A, Antonio Vetrani, Vetrani A, Lucio Palombini, Palombini L
Acta cytologica · 2005 · vol. 49(5) , pp. 495–499 · doi:10.1159/000326194 · PMID:16334025 · W2041994509
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This study evaluated fine needle cytology criteria for endometriosis diagnosis, finding that with optimal preparations and special methods, confident cytologic diagnosis is achievable and aids in treatment planning.

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Abstract

OBJECTIVE: To evaluate whether commonly used cytologic criteria for the diagnosis of endometriosis are sufficiently specific, to assess the possible role of special methods in the differential diagnosis and to assess the clinical meaning and drawbacks of a cytopathologic diagnosis of endometriosis by fine needle aspiration. STUDY DESIGN: We retrieved 10 cases of endometriosis from our files that had been diagnosed primarily by fine needle cytology (FNC) with subsequent tissue study. In some cases additional cytospin preparations and/or smears had been used for cytochemistry (periodic acid-Schiff stain, mucicarmine) or immunocytochemistry (pan-cytokeratin, cytokeratin 7, vimentin, CD10) using a 3-step streptavidin-biotin-immunoperoxidase reaction. RESULTS: The cell pattern and immunocytochemical profile of the cases suggested a diagnosis of endometriosis. All cases were histologically confirmed. CONCLUSION: With optimal preparations a confident cytologic diagnosis of endometriosis may be made with ease, permitting correct treatment of the disease and, in selected cases, planning of preoperative pharmacologic therapy.

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Condition tags

endometriosis

MeSH descriptors

Abdominal Cavity Biomarkers, Tumor Endometriosis Endometrium Epithelial Cells Abdominal Cavity Abdominal Cavity Abdominal Wall Abdominal Wall Abdominal Wall Adult Biomarkers, Tumor Biopsy, Fine-Needle Carcinoma Carcinoma Diagnosis, Differential Endometriosis Endometrium Epithelial Cells Female

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (28)

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