Fine‐needle aspiration cytology of abdominal wall endometriosis

Kim JY, Jung Yeon Kim, Ji Eun Kwon, Kwon JE, Hyun Jung Kim, Hyun-Jung Kim, Kim HJ, Kyeongmee Park, Park K
Diagnostic cytopathology · 2011 · vol. 41(2) , pp. 115–119 · doi:10.1002/dc.21779 · PMID:21987456 · W1585003743
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This study evaluated 10 cases of abdominal wall endometriosis diagnosed by fine-needle aspiration cytology, finding characteristic epithelial and stromal cells alongside macrophages and variable inflammatory cells.

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Abstract

While about 15% of menstruating women develop endometriosis, abdominal wall endometriosis is relatively rare. We present 10 cases of abdominal wall endometriosis diagnosed by fine-needle aspiration (FNA) cytology and confirmed by subsequent surgical excision. A palpable abdominal wall mass was the most common symptom, followed by pain. Nine cases were associated with previous surgery. The smear showed glandular epithelial cells and spindle or ovoid stromal cells accompanied by macrophages in eight cases. The nucleus was round-to-oval and the nucleolus was inconspicuous. Mitosis was not observed in any case. In two cases, which were suspicious of malignancy on FNA, the epithelial cells showed anisonucleosis, hyperchromasia, and small conspicuous nucleoli. The stromal cells were spindle or ovoid in shape, without metaplastic changes. Histiocytes were noted in nine cases and hemosiderin-laden histiocytes were noted in two cases. The proportion of inflammatory cells varied. FNA diagnosis of abdominal wall endometriosis is possible when the cytological features are interpreted cautiously, together with the patient's clinical history. An accurate diagnosis on FNA will prevent unnecessary surgery.

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Condition tags

endometriosis

MeSH descriptors

Abdominal Wall Endometriosis Abdominal Wall Adult Biopsy, Fine-Needle Cell Nucleolus Cell Nucleolus Cell Nucleus Cell Nucleus Endometriosis Epithelial Cells Epithelial Cells Female Hemosiderin Hemosiderin Histiocytes Histiocytes Humans Mitosis Stem Cells

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