OVARYAN ENDOMETROZİSDE D VİTAMİNİ DÜZEYLERİ

Ozlem GURSOY, Ceren Yıldız Eren, Hulusi Göktuğ GÜRER
In: Health Care Academician Journal · 2022 · doi:10.52880/sagakaderg.1104058 · W4294286572
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study found a significant moderate correlation between blood vitamin D levels and endometriosis stage, with lower vitamin D negatively impacting stage severity.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-08 · read from full text ⓘ

This study investigated the relationship between ovarian endometriosis (“endometrosis” of the ovary) and blood vitamin D levels, examining correlations with endometriosis stage, anti-Müllerian hormone, laterality (right/left), extent of disease, and infertility status, alongside socio-demographic variables (age, parity, smoking). Using descriptive statistics with correlation and regression analyses plus t-tests and one-way ANOVA, the authors found a statistically significant moderate association between vitamin D level and stage, and a regression model indicating vitamin D had a negative, significant effect on stage. The paper’s main limitation is that it does not specify any explicit causal design or control for confounding beyond the listed variables, so findings are correlational. This paper is centrally about endometriosis — specifically ovarian endometriosis and how vitamin D levels relate to disease stage.

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Abstract

ABSTRACT Introduction & Aim: The potential role of vitamin D in the pathogenesis of endometriosis is a subject that has been studied by researchers. This study was carried out to investigate the correlation between various features of endometriosis and vitamin D levels. Material Methods: Age, parity and smoking variables of the participants were examined as socio-demographic characteristics. Other variables examined in our study are stage, anti-Müllerian hormone and vitamin D levels, the side where endometriosis is seen, either right or left, the extent of endometriosis and infertility status. Descriptive statistical methods, correlation analysis, regression analysis, independent samples t-test and one-way analysis of variance were used. Results: According to the correlation analysis, there is a statistically significant, moderate relationship between the level of vitamin D in the blood and the stage. According to the regression model, vitamin D in the blood has a negative and significant effect on the stage. According to these findings, it can be said that the decrease in vitamin D level will increase the stage status of the patient. Conclusions: The correlation between vitamin D and endometriosis, which is the primary subject of the research, was investigated with three different statistical methods.
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Abstract

Introduction & Aim: The potential role of vitamin D in the pathogenesis of endometriosis is a subject that has been studied by researchers. This study was carried out to investigate the correlation between various features of endometriosis and vitamin D levels.

Material

Methods: Age, parity and smoking variables of the participants were examined as socio-demographic characteristics. Other variables examined in our study are stage, anti-Müllerian hormone and vitamin D levels, the side where endometriosis is seen, either right or left, the extent of endometriosis and infertility status. Descriptive statistical methods, correlation analysis, regression analysis, independent samples t-test and one-way analysis of variance were used.

Results

According to the correlation analysis, there is a statistically significant, moderate relationship between the level of vitamin D in the blood and the stage. According to the regression model, vitamin D in the blood has a negative and significant effect on the stage. According to these findings, it can be said that the decrease in vitamin D level will increase the stage status of the patient.

Conclusions

The correlation between vitamin D and endometriosis, which is the primary subject of the research, was investigated with three different statistical methods. Anahtar Kelimeler Destekleyen Kurum yok Proje Numarası yok Kaynakça - 1. Chapron C, Marcellin L, Borghese B, Santulli P. (2019) Rethinking mechanisms, diagnosis and management of endometriosis. Nat Rev Endocrinol, 15(11):666–82. - 2. Czyzyk A, Podfigurna A, Szeliga A, Meczekalski B. (2017) Update on endometriosis pathogenesis. Minerva Ginecol, 69(5):447–61. - 3. Sizar O, Khare S, Goyal A, Bansal P, Givler A. (2022).Vitamin D Deficiency. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. - 4. Kalaitzopoulos DR, Lempesis IG, Athanasaki F, Schizas D, Samartzis EP, Kolibianakis EM, et al. (2020) Association between vitamin D and endometriosis: a systematic review. Hormones (Athens), 19(2):109–21. - 5. Han SJ, O’Malley BW. (2014) The dynamics of nuclear receptors and nuclear receptor coregulators in the pathogenesis of endometriosis. Hum Reprod Update, 20(4):467–84. - 6. Harris HR, Chavarro JE, Malspeis S, Willett WC, Missmer SA. (2013) Dairy-food, calcium, magnesium, and vitamin D intake and endometriosis: a prospective cohort study. Am J Epidemiol, 177(5):420–30. - 7. Giampaolino P, Della Corte L, Foreste V, Bifulco G. (2019) Is there a Relationship Between Vitamin D and Endometriosis? An Overview of the Literature. Curr Pharm Des, 25(22):2421–7. - 8. Chauhan K, Shahrokhi M HM. (2021) Vitamin D. StatPearls. Treasure Island (FL): StatPearls Publishing. Ayrıntılar Birincil Dil İngilizce Konular Sağlık Kurumları Yönetimi Bölüm Klinik Araştırma Yayımlanma Tarihi 1 Eylül 2022 Gönderilme Tarihi 15 Nisan 2022 Kabul Tarihi 10 Temmuz 2022 Yayımlandığı Sayı Yıl 2022 Cilt: 9 Sayı: 3 APA Gursoy, O., Yıldız Eren, C., & Gürer, H. G. (2022). The relationship between ovarian endometrosis and vitamin D level. Sağlık Akademisyenleri Dergisi, 9(3), 265-271. https://doi.org/10.52880/sagakaderg.1104058 AMA 1.Gursoy O, Yıldız Eren C, Gürer HG. The relationship between ovarian endometrosis and vitamin D level. SagAkaDerg. 2022;9(3):265-271. doi:10.52880/sagakaderg.1104058 Chicago Gursoy, Ozlem, Ceren Yıldız Eren, ve Hulusi Göktuğ Gürer. 2022. “The relationship between ovarian endometrosis and vitamin D level”. Sağlık Akademisyenleri Dergisi 9 (3): 265-71. https://doi.org/10.52880/sagakaderg.1104058. EndNote Gursoy O, Yıldız Eren C, Gürer HG (01 Eylül 2022) The relationship between ovarian endometrosis and vitamin D level. Sağlık Akademisyenleri Dergisi 9 3 265–271. IEEE [1]O. Gursoy, C. Yıldız Eren, ve H. G. Gürer, “The relationship between ovarian endometrosis and vitamin D level”, SagAkaDerg, c. 9, sy 3, ss. 265–271, Eyl. 2022, doi: 10.52880/sagakaderg.1104058. ISNAD Gursoy, Ozlem - Yıldız Eren, Ceren - Gürer, Hulusi Göktuğ. “The relationship between ovarian endometrosis and vitamin D level”. Sağlık Akademisyenleri Dergisi 9/3 (01 Eylül 2022): 265-271. https://doi.org/10.52880/sagakaderg.1104058. JAMA 1.Gursoy O, Yıldız Eren C, Gürer HG. The relationship between ovarian endometrosis and vitamin D level. SagAkaDerg. 2022;9:265–271. MLA Gursoy, Ozlem, vd. “The relationship between ovarian endometrosis and vitamin D level”. Sağlık Akademisyenleri Dergisi, c. 9, sy 3, Eylül 2022, ss. 265-71, doi:10.52880/sagakaderg.1104058. Vancouver 1.Ozlem Gursoy, Ceren Yıldız Eren, Hulusi Göktuğ Gürer. The relationship between ovarian endometrosis and vitamin D level. SagAkaDerg. 01 Eylül 2022;9(3):265-71. doi:10.52880/sagakaderg.1104058

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