Androgen receptor cytosine, adenine, and guanine trinucleotide repeat polymorphism in Korean patients with endometriosis: A case-control study

Jae Jun Shin, Shin JJ, Choi YM, Young Min Choi, Choi HY, Hwa Young Choi, Soo Jin Chae, Hwang K, Kyuri Hwang, Jin Ju Kim, Jinju Kim, Kim JJ, Lee GH, Gyoung Hoon Lee, Kim JM, Jong Mi Kim
European journal of obstetrics, gynecology, and reproductive biology · 2017 · vol. 218 , pp. 1–4 · doi:10.1016/j.ejogrb.2017.09.005 · PMID:28915409 · W2751216286
Observational OA: closed CC0 ⤵ 5 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-09 ⓘ

This case-control study investigated the association between androgen receptor trinucleotide repeat polymorphisms (CAG, AAA, and GGN) and endometriosis in Korean patients.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

STUDY OBJECTIVE: To investigate the association between the androgen receptor (AR) cytosine, adenine, and guanine (CAG) repeat polymorphisms and endometriosis. STUDY DESIGN: A prospective case-control, genetic association study was performed on women with surgically proven endometriosis (n=421) and controls free of endometriosis (n=349). AR CAG repeat lengths were determined from peripheral blood samples. The difference in the frequency of each alleles were compared in patients with endometriosis and controls using Chi-square test. MAIN RESULTS: No significant difference in biallelic length mean between patients and controls was observed. Alleles containing 24 CAG repeats were significantly more frequent in stage I-II (mild) endometriosis than in the control samples (19.8% and 13.3%, respectively; OR 1.60, 95% CI 1.04-2.47). Additionally, a higher frequency of both alleles with 24 or more CAG repeats was observed in individuals with mild endometriosis, in comparison with the controls (25.6% and 15.2%, respectively; OR 1.92, 95% CI 1.09-3.38). CONCLUSIONS: AR gene CAG repeat polymorphisms are associated with the increased risk of mild endometriosis.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Adenine Adenine Cytosine Cytosine Endometriosis Guanine Guanine Polymorphism, Genetic Polymorphism, Genetic Receptors, Androgen Trinucleotide Repeats Alleles Alleles Case-Control Studies Case-Control Studies Chi-Square Distribution Chi-Square Distribution Endometriosis Endometriosis Endometriosis

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (25)

Cited by (5)

Source provenance

europepmc
last seen: 2026-10-13T06:10:10.580696+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:20:36.982799+00:00
unpaywall
last seen: 2026-10-13T06:25:51.201866+00:00
License: CC0 · commercial use OK