Effects of nafarelin versus danazol on lipids and calcium metabolism
Non-randomised trial
OA: closed
CC0
⤵ 13 in-corpus citations
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This study investigated the effects of nafarelin and danazol on lipid profiles and calcium metabolism in participants.
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Abstract
This 6-month clinical trial with an additional 12-month follow-up compared the effects of treatment with the gonadotropin-releasing hormone agonist nafarelin and the androgenic agent danazol on lipids and calcium metabolism in women with endometriosis. Of the 23 women who completed the double-blind, double-dummy study, 15 were treated with nafarelin and 8 with danazol. Investigators observed the effects of both agonists on estradiol levels, American Fertility Society endometriosis scores, and side effects. Results indicate that nafarelin seems to be a good alternative to other medications for the treatment of endometriosis and has an acceptable side-effect profile, including metabolic effects.
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References (4)
- Administration of nasal nafarelin as compared with oral danazol for endometriosis. A multicenter double-blind comparative clinical trial via openalex
- Gonadotrophin releasing hormone analogues for gynaecological disorders and infertility via openalex
- New therapy for endometriosis via openalex
- W2034968441 via openalex
Cited by (11)
- Gonadotropin-releasing hormone analogues for endometriosis 2023
- Gonadotrophin-releasing hormone analogues for pain associated with endometriosis 2010
- Ovulation suppression for endometriosis for women with subfertility 2007
- Ovulation suppression for endometriosis 2003
- WITHDRAWN: Gonadotrophin-releasing hormone analogues for pain associated with endometriosis 1999
- Gonadotrophin-releasing hormone analogues for pain associated with endometriosis 1999
- Today's treatments: medical, surgical and in partnership 1999
- GnRH agonists and add-back therapy: is there a perfect combination? 1998
- Effects of a gonadotropin-releasing hormone agonist on the calcium-parathyroid axis and bone turnover in women with endometriosis 1995
- A risk benefit assessment of drugs used in the treatment of endometriosis 1994
- Principles of medical therapy for endometriosis pain 1992
Source provenance
- europepmc
- last seen: 2026-10-13T06:10:10.580696+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:08:38.374512+00:00
- unpaywall
- last seen: 2026-10-13T06:25:51.201866+00:00
License: CC0
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