Progesterone-dependent regulation of endometrial cannabinoid receptor type 1 (CB1-R) expression is disrupted in women with endometriosis and in isolated stromal cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
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This study investigated progesterone's regulation of endometrial CB1-R expression, finding it disrupted in endometriosis and in stromal cells exposed to TCDD.
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References (78)
- Developmental exposure of mice to TCDD elicits a similar uterine phenotype in adult animals as observed in women with endometriosis via openalex
- Dioxin and Endometrial Progesterone Resistance via openalex
- Dioxin-like PCBs and Endometriosis via openalex
- Dioxin may promote inflammation-related development of endometriosis via openalex
- Endometriosis via openalex
- Endometriosis expresses a molecular pattern consistent with decreased retinoid uptake, metabolism and action via openalex
- Experimental Endometriosis via openalex
- Immune interactions in endometriosis via openalex
- Progesterone analogues similarly modulate endometrial matrix metalloproteinase-1 and matrix metalloproteinase-3 and their inhibitor in a model for long-term contraceptive effects via openalex
- Progesterone Receptor Isoform A But Not B Is Expressed in Endometriosis via openalex
- Reduced progesterone action during endometrial maturation: A potential risk factor for the development of endometriosis via openalex
- Steroid and Cytokine Regulation of Matrix Metalloproteinase Expression in Endometriosis and the Establishment of Experimental Endometriosis in Nude Mice via openalex
- Suppression of matrix metalloproteinases inhibits establishment of ectopic lesions by human endometrium in nude mice. via openalex
- The Pains of Endometriosis via openalex
- W1996371391 via openalex
- W1999203299 via openalex
- W2002687754 via openalex
- W2007075037 via openalex
- W2012586603 via openalex
- W2015401786 via openalex
- W2019906922 via openalex
- W2021942629 via openalex
- W2026679002 via openalex
- W2028659031 via openalex
- W2031212289 via openalex
- W2040451666 via openalex
- W2048050019 via openalex
- W2052372081 via openalex
- W2053321628 via openalex
- W2053985016 via openalex
- W2067864509 via openalex
- W2068949598 via openalex
- W2069518482 via openalex
- W2075006146 via openalex
- W2075011152 via openalex
- W2079774577 via openalex
- W2081642281 via openalex
- W2082084857 via openalex
- W2082793817 via openalex
- W2084764099 via openalex
- W2094028547 via openalex
- W2095193282 via openalex
- W2107277218 via openalex
- W2108375974 via openalex
- W2117326208 via openalex
- W2119096618 via openalex
- W2129717778 via openalex
- W2134078159 via openalex
- W2134753968 via openalex
- W2138438714 via openalex
- W2138747786 via openalex
- W2139546732 via openalex
- W2139773756 via openalex
- W2144696019 via openalex
- W2156019215 via openalex
- W2158816152 via openalex
- W2164335326 via openalex
- W2164574710 via openalex
- W2406818453 via openalex
- W3021347101 via openalex
- W4211081176 via openalex
- W6635234022 via openalex
- W6656140975 via openalex
- W6658221620 via openalex
- W6677368020 via openalex
- W1491385557 via openalex
- W1517707278 via openalex
- W1569704074 via openalex
- W1586778430 via openalex
- W1685180105 via openalex
- W1919145418 via openalex
- W1972441006 via openalex
- W1976896031 via openalex
- W1982659412 via openalex
- W1986075242 via openalex
- W1987717082 via openalex
- W1992084421 via openalex
- W1994604410 via openalex
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