Endometriosis and perceived stress: impact of surgical and medical treatment

Lucia Lazzeri, Cinzia Orlandini, Orlandini C, Silvia Vannuccini, Serena Pinzauti, Pinzauti S, Claudia Tosti, Errico Zupi, Rosella Elena Nappi, Rossella E. Nappi, Felice Petraglia
Gynecologic and obstetric investigation · 2015 · vol. 79(4) , pp. 229–233 · doi:10.1159/000368776 · PMID:25591624 · W1980573755
Non-randomised trial OA: closed CC0 ⤵ 22 in-corpus citations
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This study found that women with long-term endometriosis experienced increased perceived stress with repeated surgeries, while progestin treatment was associated with lower stress compared to gonadotropin-releasing hormone therapy.

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Abstract

BACKGROUND: The aim of the study was to investigate the levels of perceived stress in a group of women with a long-term history of endometriosis in conjunction with surgical and/or medical treatments. METHODS: A clinical trial was conducted at the Department of Molecular and Developmental Medicine, University of Siena, in collaboration with a non-profit association of women with endometriosis, A.P.E. Onlus. Patients (n = 204) with a previous diagnosis of endometriosis (for at least 3 years) were included in this study. Each patient completed a semi-structured questionnaire and a validated scale to assess perceived stress, the Perceived Stress Scale (PSS) by e-mail. RESULTS: The study showed that in women with a long-term history of endometriosis, the level of perceived stress was increased by repeated surgical treatments and reduced by some medical treatments. The median PSS value was 23 (range 9-36) and 30.6% of the study population were included in the highest stress category (>26). The highest levels were found in patients who had undergone the most surgery. The use of progestins was associated with a lower perceived stress (p = 0.004) than in the patients treated with gonadotropin-releasing hormones. CONCLUSIONS: Long-term endometriosis has a relevant impact on perceived stress, in particular in those undergoing repeated surgery.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Gonadotropin-Releasing Hormone Gynecologic Surgical Procedures Progestins Stress, Psychological Adult Adult Comorbidity Comorbidity Endometriosis Endometriosis Endometriosis Female Female Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone Gynecologic Surgical Procedures Gynecologic Surgical Procedures Humans

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (39)

Cited by (23)

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