Endometriosis and Perceived Stress: Impact of Surgical and Medical Treatment

Lucia Lazzeri, Cinzia Orlandini, Silvia Vannuccini, Serena Pinzauti, Claudia Tosti, Errico Zupi, Rosella Elena Nappi, Rossella E. Nappi, Felice Petraglia
Gynecologic and obstetric investigation · 2015 · vol. 79(4) , pp. 229–233 · doi:10.1159/000368776 · PMID:25591624 · W1980573755
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This study found that women with long-term endometriosis experienced increased perceived stress with repeated surgeries, while progestin treatment was associated with lower stress compared to gonadotropin-releasing hormone therapy.

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Abstract

BACKGROUND: The aim of the study was to investigate the levels of perceived stress in a group of women with a long-term history of endometriosis in conjunction with surgical and/or medical treatments. METHODS: A clinical trial was conducted at the Department of Molecular and Developmental Medicine, University of Siena, in collaboration with a non-profit association of women with endometriosis, A.P.E. Onlus. Patients (n = 204) with a previous diagnosis of endometriosis (for at least 3 years) were included in this study. Each patient completed a semi-structured questionnaire and a validated scale to assess perceived stress, the Perceived Stress Scale (PSS) by e-mail. RESULTS: The study showed that in women with a long-term history of endometriosis, the level of perceived stress was increased by repeated surgical treatments and reduced by some medical treatments. The median PSS value was 23 (range 9-36) and 30.6% of the study population were included in the highest stress category (>26). The highest levels were found in patients who had undergone the most surgery. The use of progestins was associated with a lower perceived stress (p = 0.004) than in the patients treated with gonadotropin-releasing hormones. CONCLUSIONS: Long-term endometriosis has a relevant impact on perceived stress, in particular in those undergoing repeated surgery.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Gonadotropin-Releasing Hormone Gynecologic Surgical Procedures Progestins Stress, Psychological Adult Comorbidity Endometriosis Endometriosis Female Gonadotropin-Releasing Hormone Gynecologic Surgical Procedures Humans Progestins Stress, Psychological Stress, Psychological

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