A Case of Appendiceal Endometriosis Not Diagnosed Preoperatively

In: Nippon Daicho Komonbyo Gakkai Zasshi · 2023 · vol. 76(4) , pp. 359–364 · doi:10.3862/jcoloproctology.76.359 · W4361801975
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AI-generated summary by claude@2026-06, 2026-06-08

This case report describes a 47-year-old woman with an appendix intussusception due to endometriosis, which was difficult to diagnose preoperatively despite imaging and endoscopic findings.

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AI-generated deep summary by claude@2026-06, 2026-06-10 · read from full text

The paper reports a 47-year-old woman with lower abdominal pain who had been scheduled for surgery for a left ovarian endometriosis-related cyst, but abdominal CT instead showed an enlarged appendix with elevated CA19-9 and a protruding lesion at the appendiceal orifice on lower endoscopy. Because preoperative diagnosis was difficult, the authors performed laparoscopic appendiceal partial resection simultaneously with gynecologic surgery; pathology showed PAX8 positivity, CD10 positivity, and estrogen receptor-positive endometriosis-like stromal tissue with fibrous connective tissue proliferation and the appendix wall invaginating into the lumen, producing appendiceal intussusception. The case highlights the rarity of endometriosis with intussusception and the limited ability to diagnose it preoperatively, which is the main explicit caveat. This paper is centrally about endometriosis — it is a case report of appendiceal endometriosis presenting with appendiceal intussusception that was not diagnosed before surgery.

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Abstract

症例は47歳女性,主訴は下腹部痛であった.左卵巣子宮内膜症性嚢胞で手術予定であったが下腹部痛を認めたため腹部CT検査を施行したところ虫垂腫大を指摘された.血液検査所見でCA19-9は208U/mLと高値であり,下部内視鏡検査では虫垂開口部より隆起性病変を認めたが生検結果はGruop1であった.以上より診断目的に婦人科手術と同時に腹腔鏡下盲腸部分切除術を施行した.病理組織学的検査でpaired box(PAX)8(+)の立方上皮と上皮下にcluster of differentiation(CD)10(+),エストロゲン受容体〈Estrogen Receptor;ER〉(+)の内膜様間質組織を認め,線維性結合組織の増生で虫垂壁は内腔に向かって内反し,虫垂重積を伴う子宮内膜症の診断であった.重積を伴う子宮内膜症はまれであり,術前診断は困難である.今回,重積を伴う虫垂子宮内膜症の1例を経験したので文献的考察を加えて報告する.
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症例報告 術前診断に難渋した虫垂子宮内膜症による虫垂重積の1切除例 2023 年 76 巻 4 号 p. 359-364 詳細 抄録 症例は47歳女性,主訴は下腹部痛であった.左卵巣子宮内膜症性嚢胞で手術予定であったが下腹部痛を認めたため腹部CT検査を施行したところ虫垂腫大を指摘された.血液検査所見でCA19-9は208U/mLと高値であり,下部内視鏡検査では虫垂開口部より隆起性病変を認めたが生検結果はGruop1であった.以上より診断目的に婦人科手術と同時に腹腔鏡下盲腸部分切除術を施行した.病理組織学的検査でpaired box(PAX)8(+)の立方上皮と上皮下にcluster of differentiation(CD)10(+),エストロゲン受容体〈Estrogen Receptor;ER〉(+)の内膜様間質組織を認め,線維性結合組織の増生で虫垂壁は内腔に向かって内反し,虫垂重積を伴う子宮内膜症の診断であった.重積を伴う子宮内膜症はまれであり,術前診断は困難である.今回,重積を伴う虫垂子宮内膜症の1例を経験したので文献的考察を加えて報告する. © 2023 日本大腸肛門病学会 この記事はクリエイティブ・コモンズ [表示 - 非営利 - 改変禁止 4.0 国際]ライセンスの下に提供されています。 https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja

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endometriosis

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